Pathology of Coronary Chronic Total Occlusion

Kenichi Sakakura; Kazuyuki Yahagi; Renu Virmani; Michael Joner

International Cardiovascular Research Journal

The Official Annually Journal of Cardiovascular Research Center, Shiraz University of Medical Sciences

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Pathology of Coronary Chronic Total Occlusion

Author(s):

Kenichi Sakakura¹,

Kazuyuki Yahagi¹,

Renu Virmani¹,

Michael Joner^1,*

1CVPath Institute, Gaithersburg, United States

International Cardiovascular Research Journal:Vol. 10, issue 2; e10279

Published online:Jun 01, 2016

Article type:Review Article

Received:Jun 24, 2015

Accepted:Oct 12, 2015

How to Cite:Kenichi SakakuraKazuyuki YahagiRenu VirmaniMichael JonerPathology of Coronary Chronic Total Occlusion.Int Cardiovasc Res J.10(2):e10279.

Abstract

There is an increasing need for percutaneous revascularization procedures of coronary Chronic Total Occlusion (CTO), because many patients with severe coronary artery disease have limited options for revascularization. Although the success rate of percutaneous revascularization of CTOs was unsatisfactory from the 1990s to the 2000s, recent technological advances in interventional strategies have improved the success rate to 85%. Detailed histological assessment of human autopsy studies of CTO has contributed significantly to the refinement in Percutaneous Coronary Intervention (PCI) techniques and device development. We have recently reported the pathological findings and characteristics of CTOs that occur in different clinical scenarios. In this review, we discuss the pathology of CTOs to facilitate greater understanding of revascularization strategies for CTOs.

Keywords

Occlusion

Pathology

Percutaneous Coronary Intervention

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