Relationship between Renal Artery Stenosis and Severity of Coronary Artery Disease in Patients with Coronary Atherosclerotic Disease

Amirfarhang  Zandparsa; Mehrdad  Habashizadeh; Ehsan  Moradi Farsani; Mostafa  Jabbari; Razieh  Rezaei

International Cardiovascular Research Journal

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Relationship between Renal Artery Stenosis and Severity of Coronary Artery Disease in Patients with Coronary Atherosclerotic Disease

Author(s):

Amirfarhang Zandparsa¹,

Mehrdad Habashizadeh^1,*,

Ehsan Moradi Farsani¹,

Mostafa Jabbari¹,

Razieh Rezaei¹

1Department of Cardiology, Tehran University of Medical Sciences, Tehran, Iran

International Cardiovascular Research Journal:Vol. 6, issue 3; e12803

Published online:Sep 30, 2012

Article type:Research Article

Received:May 16, 2017

Accepted:Jul 12, 2012

How to Cite:Zandparsa A, Habashizadeh M, Moradi Farsani E, Jabbari M, Rezaei R. Relationship between Renal Artery Stenosis and Severity of Coronary Artery Disease in Patients with Coronary Atherosclerotic Disease.Int Cardiovasc Res J.2012;6(3):e12803.

Abstract

Objective: The aim of the present investigation was to explore probable association of renal artery stenosis (RAS) with coronary artery disease (CAD) and the prevalence of renal artery stenosis (RAS) in patients with CAD.

Patients and methods: This study comprised 165 consecutive patients with CAD, including 52.7% males and 47.2% females with respective mean ages of 60.3 ±8.9 and 59.5±10.1. The patients underwent simultaneous coronary and renal angiographies, and the lumen reduction of 50% or more was considered as significant stenosis. Indeed, stenosis of more than 70% of the arterial lumen was regarded as severe.

Results: According to our findings, the prevalence of renal artery stenosis in our hypertensive and normotensive patients were 46.2% and 19.5% respectively (p=0.002). Renal artery angiography revealed that 64 (38.8%) of the patients had simultaneous renal artery stenosis. RAS is more common in females than males (p=0.031). Multivariate analysis revealed that among all examined factors, hypertension and serum creatinine were associated with RAS. There was no correlations found between gensini score and RAS (p=0.63).

Conclusion: We found a relatively high prevalence of RAS including 46.2% in hypertensive and 19.5% in normotensive patients in our patients with CAD.

Keywords

Coronary Artery Disease

Renal Artery Stenosis

Hypertension

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