Since cardiac involvement in scleroderma patients has a poor prognosis, studies have shown that observation of Left Ventricular (LV) deformation analysis using the sensitive speckle-tracking echocardiography (STE) method is appropriate in predicting heart failure.
This study evaluated LV function in patients with scleroderma with normal pulmonary artery pressure.
This cross-sectional study was performed on 30 scleroderma patients and 30 healthy cases by myocardial strain analysis. The frequency of left ventricular dysfunction in systemic sclerosis patients was evaluated by STE, two-dimensional (2D) echocardiography, and Tissue Doppler Imaging (TDI). The statistics analysis was done by SPSS software version 22.
The mean age was 41.07 ± 8.94 years in the case group and 39.00 ± 15.64 years in the control group. The absolute values of the global longitudinal strain (GLS) average, GLS average 3-chambers, ejection fraction, end-diastolic volume (EDV), and stroke volume were significantly lower in the case group compared with the control group (P < 0.05). The two groups were similar in other echocardiographic indicators including GLS average 2-chambers, GLS average 4-chambers, heart rate, PAP (mm), and end-systolic volume (ESV) (P > 0.05).