Comparison of the Cost-Effectiveness of Transesophgeal and Transthoracic Echocardiographies to Detect Cardioembolic Causes of Stroke in Non-Selected Patients

Ramin  Ravangard; Abdosaleh Jafari; Iman  Rahgoshai; Mahmoud Zamirian; Kamran  Aghasadeghi; Alireza  Moarref; Golnaz  Yadollahikhales; Salvador Cruz-Flores; mojtaba neydavoodi; Afshin  Borhani-Haghighi

International Cardiovascular Research Journal

The Official Annually Journal of Cardiovascular Research Center, Shiraz University of Medical Sciences

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Comparison of the Cost-Effectiveness of Transesophgeal and Transthoracic Echocardiographies to Detect Cardioembolic Causes of Stroke in Non-Selected Patients

Author(s):

Ramin Ravangard¹,

Abdosaleh Jafari²,

Iman Rahgoshai¹,

Mahmoud Zamirian³,

Kamran Aghasadeghi³,

Alireza Moarref⁴,

Golnaz Yadollahikhales⁵,

Salvador Cruz-Flores⁵,

mojtaba neydavoodi⁶,

Afshin Borhani-Haghighi^6,*

1Health Human Resources Research Center, School of Management and Medical Information Sciences, Shiraz University of Medical Sciences, Shiraz, Iran

2Health Management and Economics Research Center, Iran University of Medical Sciences, Tehran, Iran

3Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

4Iran

5Department of Neurology, Texas Tech University, El Paso, United States

6Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

International Cardiovascular Research Journal:Vol. 12, issue 2; e61352

Published online:Jun 30, 2018

Article type:Research Article

Received:May 20, 2018

Accepted:Apr 08, 2018

How to Cite:Ramin RavangardAbdosaleh JafariIman RahgoshaiMahmoud ZamirianKamran AghasadeghiAlireza MoarrefGolnaz YadollahikhalesSalvador Cruz-Floresmojtaba neydavoodiAfshin Borhani-Haghighiet al.Comparison of the Cost-Effectiveness of Transesophgeal and Transthoracic Echocardiographies to Detect Cardioembolic Causes of Stroke in Non-Selected Patients.Int Cardiovasc Res J.12(2):e61352.

Abstract

Background:

Both Transthoracic Echocardiography (TTE) and Transesophgeal Echocardiography (TEE) are effective investigation tools to detect cardioaortic sources of embolism in ischemic stroke. Nevertheless, there are still uncertainties about the cost-effectiveness of these methods in non-selected patients with acute stroke.

Objectives:

This study aimed to investigate the cost-effectiveness of TTE and TEE using a decision analytic model in non-selected patients with acute ischemic stroke with or without clinical and radiological signs of embolic pattern.

Patients and Methods:

This cross-sectional cost-effectiveness study was performed in Nemazee hospital affiliated to Shiraz University of Medical Sciences from January 2014 to April 2014. TTE and TEE were performed for all 65 consecutive patients with ischemic stroke (51.3% male, mean age of 69.7 ± 17.9 years). The required data were direct costs related to performance of TTE and TEE, which were obtained from the patients’ bills in their charts. A decision analytic model was implemented to assess the cost-effectiveness of these two methods, which demonstrated an Incremental Cost-Ef-fectiveness Ratio (ICER). Effectiveness was determined based on the number of disorders diagnosed using each of the two echoes confirmed by two cardiologists. All analyses were done using Tree Age Pro 2011.

Results:

The results showed that TEE was more expensive than TTE in non-selected patients. Performing TEE increased the cost by 1494 USD and the effectiveness by 7%. As per ICER equation, for each increment unit in the effectiveness, performing TEE would increase the cost by 213.4 USD compared to TTE. TEE was cost-effective in comparison to TTE regardless of age factor considering the cutoff of Gross Domestic Product (GDP) by three for ICER. Moreover, TTE was cost-effective in 41-60- and 61-80-year-old age groups, while TEE was cost-effective in the 41-60-year-old age group. However, none of the techniques was cost-effective in patients above 81 years old.

Conclusions:

The results of this study can help reduce the unnecessary use of echocardiography by considering the age group and their corresponding risk factors for developing ischemic stroke.

Keywords

Stroke

Ischemic

Embolic

Cost-Benefit Analysis

Echocardiography

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