Alcoholic Cardiomyopathy: Clinical and Molecular Findings

M  Correale; I  Laonigro; F  Altomare; MDi  Biase

International Cardiovascular Research Journal

The Official Annually Journal of Cardiovascular Research Center, Shiraz University of Medical Sciences

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Alcoholic Cardiomyopathy: Clinical and Molecular Findings

Author(s):

M Correale^1,*,

I Laonigro²,

F Altomare²,

MDi Biase¹

1Department of Cardiology, University of Foggia, Italy

2Institute of Internal Medicine, Department of Medical and Occupational Sciences University of Foggi, Italy

International Cardiovascular Research Journal:Vol. 2, issue 1; e68544

Published online:Mar 31, 2008

Article type:Review Article

Received:Mar 14, 2018

Accepted:Mar 31, 2008

How to Cite:M CorrealeI LaonigroF AltomareMDi BiaseAlcoholic Cardiomyopathy: Clinical and Molecular Findings.Int Cardiovasc Res J.2(1):e68544.

Abstract

It has been known for some decades that chronic alcoholism can lead to dilated cardiomyopathy. Although excessive
drinking is known to result in alcoholic cardiomyopathy and light-to-moderate drinking may confer some
cardiovascular benefits, recent studies suggest that it is not only the quantity, but also drinking patterns and genetic
factors, that may influence the relation between alcohol consumption and cardiovascular disease. Alcoholic
patients consuming > 90g of alcohol a day for > 5 years are at risk for the development of asymptomatic alcoholic
cardiomyopathy. Those who continue to drink may become symptomatic and develop signs and symptoms of
heart failure. We summarize the experimental and clinical evidence regarding the role of alcohol in pathophysiology
of alcoholic cardiomyopathy.

Keywords

Alcoholic Cardiomyopathy

Heart Failure

Congestive Heart Failure

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