Relationship Between Periodontal Disease and Acute Myocardial Infarction

Mahmood Zamirian; S  Raoofi; Shahdad Khosropanah; R  Javanmardi

International Cardiovascular Research Journal

The Official Annually Journal of Cardiovascular Research Center, Shiraz University of Medical Sciences

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Relationship Between Periodontal Disease and Acute Myocardial Infarction

Author(s):

Mahmood Zamirian^1,*,

S Raoofi²,

Shahdad Khosropanah²,

R Javanmardi²

1Department of cardiology, cardiovascular research center, Iran

2Faculty of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran

International Cardiovascular Research Journal:Vol. 1, issue 4; e69667

Published online:Dec 31, 2007

Article type:Research Article

Received:Apr 24, 2018

Accepted:Dec 31, 2007

How to Cite:Mahmood ZamirianS RaoofiShahdad KhosropanahR JavanmardiRelationship Between Periodontal Disease and Acute Myocardial Infarction.Int Cardiovasc Res J.2007;1(4):e69667.

Abstract

Background: Conventional risk factors for coronary artery disease and myocardial infarction do not explain all
of the clinical and epidemiological features of the disease. Periodontal disease is a common bacterial and destructive
disorder of oral tissues. Many studies demonstrate close association between chronic periodontitis and
development of generalized inflammation, vascular endothelial injury, and atherosclesis.
Periodontal disease has been convincingly emerging as an important independent risk factor for ischemic heart
disease. A case - control study was carried out to assess the prevalence of periodontitis in patients with Acute
myocardial Infarction (AMI) and evaluate the possible relationship between AMI and chronic periodontitis.
Patients and Methods: A number of 160 patients, aged 35 to 70 years old, enrolled in the study. Eighty patients
(43 men, 37 women) were examined four days after hospitalization due to AMI. Control group consisted of 80
persons (38 men, 42 women) with normal coronary angiography. The following periodontal parameters were
examined: Plaque index (PI), gingiral index (GI), bleeding on probing (BOP), probing depth (PD), clinical attachment
loss (CAL) and number of sites with CAL.
Results: The case, compared to control showed significantly worse results for some periodontal variables studied:
The mean of PD and PD > 3 mm, CAL, and number of sites with CAL, had worse results compared to control
despite similar oral hygiene and frequency of brushing. The confounding factors for the present study were found
to be hypertension and diabetes.
Conclusion: The association between periodontitis and acute myocardial infarction was significant after adjusting
for conventional risk factors for AMI.

Keywords

Coronary Artery Disease

Periodontal Disease

Acute Myocardial Infarction.

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