FFP Transfusion and Nosocomial Infection in Cardiac Surgery: A Systematic Review

Bahman Naghipour; Sajjad Ahmadi; Gholamreza Faridaalaee; Allahveirdy  Arjmand; Farzaneh  Soleimani

International Cardiovascular Research Journal

The Official Annually Journal of Cardiovascular Research Center, Shiraz University of Medical Sciences

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FFP Transfusion and Nosocomial Infection in Cardiac Surgery: A Systematic Review

Author(s):

Bahman Naghipour

¹,

Sajjad Ahmadi

²,

Gholamreza Faridaalaee

^3,*,

Allahveirdy Arjmand

⁴,

Farzaneh Soleimani

⁵

1Department of Anesthesiology and Critical Care, Tabriz University of Medical Sciences, Tabriz, IR Iran

2Department of Emergency Medicine, Tabriz University of Medical Sciences, Tabriz, IR Iran

3Department of Emergency Medicine, Maragheh University of Medical Sciences, Maragheh, IR Iran

4Department of Anesthesiology, Maragheh University of Medical Sciences, Maragheh, IR Iran

5Department of Nursing, Maragheh University of Medical Sciences, Maragheh, Iran

International Cardiovascular Research Journal:Vol. 13, issue 4; e98088

Published online:Dec 01, 2019

Article type:Review Article

Received:Sep 14, 2019

Accepted:Nov 11, 2019

How to Cite:Naghipour B, Ahmadi S, Faridaalaee G, Arjmand A, Soleimani F. FFP Transfusion and Nosocomial Infection in Cardiac Surgery: A Systematic Review.Int Cardiovasc Res J.2019;13(4):e98088.

Abstract

Context:

In some studies, Fresh Frozen Plasma (FFP) transfusion in severely ill patients was accompanied with an increase in the risk of nosocomial infection. However, there are no comprehensive data in terms of FFP transfusion and its relationship with nosocomial infection in heart surgery. Hence, the present systematic review and meta-analysis aimed to investigate the relationship between FFP transfusion and nosocomial infection risk in the patients undergoing cardiac surgery.

Evidence Acquisition:

Study selection: The present study included all the studies, which probed into nosocomial infection after FFP transfusion in patients with cardiac surgery.

Data sources: Medline, Web of Science, Embase, Central, and Scopus electronic databases were searched to the end of March 2019.

Results:

Finally, five articles and three abstracts that studied nosocomial infection were entered into the present systematic review. FFP increased the rate of nosocomial infection in cardiac surgery in one article, but this was not the case in the remaining four articles. The three abstracts also reported that FFP increased the rate of nosocomial infection in cardiac surgery.

Conclusion:

The studies indicated that the benefit of FFP administration outweighed the probable risk of infection. Indeed, none of the studies indicated a strong relationship between FFP transfusion and infection rate after cardiac surgery.

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Author(s):

Bahman Naghipour:[PubMed][Scholar]
Sajjad Ahmadi:[PubMed][Scholar]
Gholamreza Faridaalaee:[PubMed][Scholar]
Allahveirdy Arjmand:[PubMed][Scholar]
Farzaneh Soleimani:[PubMed][Scholar]