Journal of Inflammatory Diseases
The Official Journal of Qazvin University of Medical Sciences
Isolation of T. gondii from the brain of mammalian and birds and its lethal effect on mice
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Abstract
Background: Recognition of the biological, antigenic and genetic characteristics od T. gondii isolated in our country demands more attention in the area of research. Objective: To isolate T. gondii from the brain of mamalian and birds and to identify the antigenic components of isolated strains. Methods: Isolation of T. gondii from the brain of the animals were performed by using direct smear and bioassay in mice. Findings: No tissue cysts were defected in direct smear from the brain of 46 birds and mammalian. In bioassay performed in mice, T. gondii was isolated from 40% of fowls and 14% of sheep. In general of the isolated strains were lethal for mice and the number of tissue cysts from the sheep isolates were more than fowl isolates. Conclusion: The results indicated that most of isolates were avirulence strains. Among T. gondii isolates , different number of tissue cysts were observed.
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© 2024, Journal of Inflammatory Diseases. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.
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