Prevalence of Helicobacter pylori infection in patients with stomach cancer

authors:

avatar H Forotan , avatar AK Hajagha Mohamadi , *


how to cite: Forotan H, Hajagha Mohamadi A. Prevalence of Helicobacter pylori infection in patients with stomach cancer. J Inflamm Dis. 2000;4(2):e154705. 

Abstract

Abstract Background: The role of helicobacter pylori in peptic ulcer suggests the probable role of this infection in stomach cancer. Objective: To evaluate the prevalence of H. pylori infection in patients with stomach cancer. Methods: This study was conducted in patients who referred to Emam-Khomaini hospital of Tehran in 1997. The patients had tumoral lesion in endoscopical view in which two biopsies were taken. The first biopsy was taken from lesion for pathological examination and the second one from antrum for ureas test. Findings: Out of 60 patients with definite cancer, the most prevalent area was cardia (26.6%) and the most prevalent kind of lesion was ulceractive (50%). The prevalence of H. pylori infection was totally 51.7%. H. pylori were more seen in antrum and infilterative lesions. Conclusion: Helicobacter pylori infection can have a certain role in stomach cancer specially in antrum and infilterative lesions. Keywords: Helicobacter Pylori, Stomach Cancer