Abstract
Background: Penicillin is a choice drug for treatment of streptococcal pharyngitis and is not toxic nor expensive. It is effective in all groups of streptococcus. Objective: To determine penicillin sensitivity in GABHS. Methods: 44 isolates of GABHS from 500 patients who referred to Qods hospital of Qazvin with symptoms of pharyngitis were collected to determine the frequency of antimicrobial resistance. Susceptibility testing was performed according to the guidelines of laboratory standards by the tube microdilution for penicillin. Antibiogram was performed by disk method for penicillin and 5 other antibiotics. Findings: Minimum bacterial concentration for GABHS was 0.0025 to 0.02. 100% of strains were sensitive to penicillin, amoxicilin and erythromycin but resistant to co-trimoxazole. Conclusion: Penicillin is the most effective and reliable drug for GABHS. Amoxicilin and erythromycin are recommended as choice drugs for cases of allergy.
Keywords
Penicillin Sensitivity GABHS (Group A beta hemolytic streptococus)
Copyright
© 2024, Journal of Inflammatory Diseases. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.