Comparison of neonate apgar score in two induction anesthetic techniques with thiopental and propofol in cesarean section

authors:

avatar MB Khezri , * , avatar Sh Olad Asgari


how to cite: Khezri M, Olad Asgari S. Comparison of neonate apgar score in two induction anesthetic techniques with thiopental and propofol in cesarean section. J Inflamm Dis. 2005;8(4):e155085. 

Abstract

Abstract Background: Drugs used in management of anesthesia in cesarean induce depressive effect on neonatal apgar. Objective: To determine and comparing the propofol and thiopental effects on neonate apgar score. Methods: Through a prospective single blind randomized clinical trial, sixty patients operated for cesarean section in 2002 in Qazvin Kosar hospital were randomly divided in two groups as A and B. Induction of anesthesia was carried out using thiopental 4mg/kg and propofol 2 mg/kg in groups A and B respectively. The time from the induction of anesthesia to child birth and also the time of uterus incision to child birth were measured. Neonate apgar scores were recorded. Following 1 and 5 minutes intervals. The results were analyzed using Spss soft ware and T test. Findings: The average of apgar score at 1 minute in thiopental group and propofol group were 8.83±0.379 and 8.93±0.253 respectively. The difference between group A and B was statistically insignificant. The apgar scores at minutes in two groups were 10 and statically insignificant. Based on our results there was no statistically significant difference between two groups in the time of induction of anesthesia and uterus incision to child birth. Conclusion: Propofol and Thiopental showed similar effects on neonate apgar score in cesarean.