Abstract
Abstract
Background: Studies have shown that G6PD deficiency results in indirect hyperbilirubinemia in newborns.
Objective: Determining the relationship between G6PD deficiency and neonatal hyperbilirubinemia.
Methods: Through a case-control study, 200 neonates with indirect hyperbilirubinemia were equally divided into two case and control groups and examined for G6PD deficiency using a commercial G6PD kit and a fluorometric analysis. The data were further analyzed statistically.
Findings: Results showed that out of 200 neonates, 24 had G6PD deficiency (10 in case group and 14 in control group). There was no statistically significant difference between two groups.
Conclusion: Since the prevalence of G6PD deficiency among nonicteric group (control group) was higher than the icteric group (case group), it seems that the performance of a screening test to measure the G6PD activity in all neonates to be useful.
Keywords
Key words: G6PD deficiency Indirect hyperbilirubinemia Neonate
Copyright
© 2024, Journal of Inflammatory Diseases. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.