The effect of cinnamon on glucose concentration of diabetic rats in presence or absence of insulin

N Gheibi; MR Parvizi; H Jahani Hashemi

Journal of Inflammatory Diseases

The Official Journal of Qazvin University of Medical Sciences

Current Issue All Issues In Press Accepted Manuscripts Search

Journal Information Editors & Boards Indexing and Listing Sources Reviewer and AE Registration Form Journal Metrics Open Peer Review (OPR)Publication Ethics and Publication Malpractice Statement Support Contact Us

Authors Guide Submit Manuscript

The effect of cinnamon on glucose concentration of diabetic rats in presence or absence of insulin

Author(s):

N Gheibi^,*,

MR Parvizi,

H Jahani Hashemi

Journal of Inflammatory Diseases:Vol. 9, issue 3; 3-8

Article type:Research Article

How to Cite:N GheibiMR ParviziH Jahani HashemiThe effect of cinnamon on glucose concentration of diabetic rats in presence or absence of insulin.J Inflamm Dis.9(3):e155136.

Abstract

Abstract Background: Some plants and their aqueous extracts are used as traditional treatments for diabetes. Cinnamon as a preferred candidate shows anti-diabetic and hypoglycemic effects. Objective: To determine the effect of cinnamon extract on blood glucose level of diabetic rats. Methods: The present work was an experimental study in which seventy NMRI male rats (180-250gr) were divided into 2 major groups named as normal and diabetic group. Normal group was further subdivided as control, cinnamon and insulin subgroups in which the latter two received suspensions of cinnamon 60mg/kg per day and intraperitoneal injections of insulin (5μg/kg), respectively. In four diabetic subgroups, diabetes was induced by ip injection of streptozotocin (40mg/kg). These groups were marked as diabetic control, diabetic/cinnamon, diabetic/insulin and cinnamon plus insulin subgroups. Findings: Our results showed that the oral administration of cinnamon had not significant effect on normal cinnamon subgroup. Insulin injection in normal rats reduced glucose concentration from 99.1 to 52.1 mg/dl. Glucose concentration in diabetic groups with treatment of cinnamon, Insulin and both of them were measured 121.6, 69.6 and 41.4 mg/dl, respectively. Reduction of glucose concentration in these subgroups show asignificant change in comparison with control diabetic subgroup, 366.5 mg/dl (p

Keywords

Keywords: Blood Glucose

Cinnamon

Insulin

Diabetes Mellitus

comments