Comparison of intramuscular syntometrine and intravenous oxytocin in management of the third stage of labor

F Movahed; H Abbasi

Journal of Inflammatory Diseases

The Official Journal of Qazvin University of Medical Sciences

Current Issue All Issues In Press Accepted Manuscripts Search

Journal Information Editors & Boards Indexing and Listing Sources Reviewer and AE Registration Form Journal Metrics Open Peer Review (OPR)Publication Ethics and Publication Malpractice Statement Support Contact Us

Authors Guide Submit Manuscript

Comparison of intramuscular syntometrine and intravenous oxytocin in management of the third stage of labor

Author(s):

F Movahed^,*,

H Abbasi

Journal of Inflammatory Diseases:Vol. 11, issue 2; 27-32

Article type:Research Article

How to Cite:F MovahedH AbbasiComparison of intramuscular syntometrine and intravenous oxytocin in management of the third stage of labor.J Inflamm Dis.11(2):e155298.

Abstract

Abstract Background: One of the main etiologies of maternal mortality is obstetrical hemorrhage. The first step in decreasing hemorrhage is the use of uterotonic drugs in the third stage of labor. Objective: To compare the efficacy and safety of intravenous oxytocin and intramuscular syntometrine in management of the third stage of labor. Methods: This randomized double blind clinical trial was carried out at Kosar Hospital, Qazvin (Iran) in 2005. A total of 800 women having a singleton pregnancy and vaginal delivery were randomized to receive either 1 ml of syntometrine intramuscularly, or 10 units of intravenous oxytocine following delivery of the anterior shoulder of fetus. Hemoglobin level pre- and 24 hours post-delivery, duration of third stage, need for re-administration of uterotonic drugs, need for manual removal of placenta, and unpleasant side effects including nausea, vomiting, headache and hypertension were recorded. The data were analyzed using chi-square test. Findings: Mean drop percent of hemoglobin level in oxytocin group was 3.7±2.54% and in syntometrine group 3.6±2.49% with no significant difference, statistically. There was also no statistically significant difference between the need for re-administration of uterotonic drugs, duration of third stage of labor, need for manual removal of placenta and the maternal side effect in two groups. Conclusion: Regarding the efficacy and side effects of intravenous oxytocin and intramuscular syntometrine, no difference was found.

Keywords

comments