The effect of flow divider on restenosis in stented human coronary artery with modelling

V Dehlaghi; S Najarian; M Tafazzoli Shadpour

Journal of Inflammatory Diseases

The Official Journal of Qazvin University of Medical Sciences

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The effect of flow divider on restenosis in stented human coronary artery with modelling

Author(s):

V Dehlaghi^,*,

S Najarian,

M Tafazzoli Shadpour

Journal of Inflammatory Diseases:Vol. 12, issue 2; 7-12

Article type:Research Article

How to Cite:V DehlaghiS NajarianM Tafazzoli ShadpourThe effect of flow divider on restenosis in stented human coronary artery with modelling.J Inflamm Dis.12(2):e155386.

Abstract

Abstract Background: Shear stress is known to play a central role in restenosis formation and is sensitive to stent geometry. Objective: To investigate the effec of flow divider on restenosis in a stented human coronary artery. Methods: The present paper describes a qualitative study in which a computational fluid dynamics model to analyze the blood flow in a stented human coronary artery was used. Stents were assumed with real structure and modeled using the commercial software package (Gambit, V2.0). A flow divider is a flexible cylindrical body with different diameters and lengths which is centered within the stent lumen by means of self-expandable stabilizing arms. The blood flow was modeled as an incompressible Newtonian viscous fluid. Rigid geometric boundary conditions were assumed for all simulations. The governing equations were solved using the commercial software package (Fluent, V6.0.12). Findings: The wall shear stress between stent struts was sensitive to the flow divider, and the wall shear stress distributions for different types of flow divider were calculated. Conclusion: Application of a flow divider led to noticeable increase in wall shear stress in stented segment.

Keywords

Keywords: Stent

Arteries

Computatienal Fluid Dynamics

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