Occlusal abnormalities and face changes in major β-thalassemic patients

Background: Major β-thalassemia is the most common monogenic known disorder in Iran affecting about 25000 persons. Objective: This study was performed to evaluate occlusal abnormalities and face changes in major β-thalassemic patients. Methods: This was a cross-sectional study performed on 281(162 males, 119 females) patients attending to the thalassemia center of Zahedan over a time period between May to September, 2006. All patients were evaluated for occlusal abnormality and face changes. Data were collected through questionnaires (general, dental, medical) and clinical examinations and further analyzed by chi square test. Findings: Occlusal abnormalities included open bite (3.6%), deep bite (22.4%), cross bite (5.7%), crowding (29.5%), and spacing (15.7%). Face changes resulting from major β-thalassemia were: saddle nose (60.1%), bimaxillary protrusion (25.6%), and rodent face (34.8%). There was no significant difference between the prevalence of occlusal abnormalities and face changes in both genders. Most patients (85%) were in the first and second decade of life. The prevalence of occlusal abnormalities and face changes increased with age. The common type of occlusion in studied population was class I, II, III. Early diagnosis and blood transfusion caused a decrease in prevalence of complications. Conclusion: Based on the results of present study, early diagnosis and treatment leads to lower prevalence rate of complication, occlusal abnormalities, and face changes. Attempts should be made to increase the general knowledge of parents over the children’s oral health.

Keywords

Keywords: Major β-Thalassemia

Occlusal abnormalities

Face Changes

Malocclusion in subjects with beta-thalassemia major

Fatemeh Shahsavari,

Mohammad Eslami,

MohammadHosien FarahVash

Shahsavari F, Eslami M, FarahVash M. Malocclusion in subjects with beta-thalassemia major. koomesh. 2007;8(4):e152154. doi:

13

Sep

2010

Dental health and dental treatment needs in patients with thalassemia major

Marieh Honarmand,

Narjes Amiri tehrani,

Leila Farhad-Mollashahi

Honarmand M, Amiri tehrani N, Farhad-Mollashahi L. Dental health and dental treatment needs in patients with thalassemia major. Zahedan J Res Med Sci. 2010;12(3):e94300. doi:

1

Nov

2003

Evaluation of oralmanifestation and bonelesion in patient with major thalassemia (Qazvin, 1998-99)

H Tafazzoli shadpour

Tafazzoli shadpour H. Evaluation of oralmanifestation and bonelesion in patient with major thalassemia (Qazvin, 1998-99). J Inflamm Dis. 2024;7(3):e154961. doi:

10

Feb

2018

Hypothyroidism and Hypoparathyroidism in Thalassemia Major Patients: A Study in Sistan and Baluchestan Province, Iran

Ali Bazi,

Hadi Harati,

Ali Khosravi-Bonjar,

Elham Rakhshani,

Mojtaba Delaramnasab

Bazi A, Harati H, Khosravi-Bonjar A, Rakhshani E, Delaramnasab M. Hypothyroidism and Hypoparathyroidism in Thalassemia Major Patients: A Study in Sistan and Baluchestan Province, Iran. Int J Endocrinol Metab. 2018;16(2):e13228. doi: https://doi.org/10.5812/ijem.13228

30

Apr

2008

Evaluation of Endocrine Disorders in Patients with Thalassemia Major

F Najafipour

Najafipour F. Evaluation of Endocrine Disorders in Patients with Thalassemia Major. Int J Endocrinol Metab. 2008;6(2):. doi:

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Occlusal abnormalities and face changes in major β-thalassemic patients

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