Effect of omeg-3 supplementation on preeclampsia in high risk pregnant women

F Ranjkesh; F Laluha; H Pakniat; H Kazemi; T Golshahi; s Esmaili

Journal of Inflammatory Diseases

The Official Journal of Qazvin University of Medical Sciences

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Effect of omeg-3 supplementation on preeclampsia in high risk pregnant women

Author(s):

F Ranjkesh^1,*,

F Laluha²,

H Pakniat²,

H Kazemi¹,

T Golshahi³,

s Esmaili⁴

1Qazvin University of Medical Sciences, Qazvin, Iran

2, Qazvin University of Medical Sciences, Qazvin, Iran

3Qazvin University of Medical Sciences, Qazvin, Iran

4Qazvin university of medical science,Qazvin,Iran

Journal of Inflammatory Diseases:Vol. 15, issue 2; 28-33

Article type:Research Article

How to Cite:F RanjkeshF LaluhaH PakniatH KazemiT Golshahis Esmailiet al.Effect of omeg-3 supplementation on preeclampsia in high risk pregnant women.J Inflamm Dis.15(2):e155612.

Abstract

Background: Identification of factors preventing preeclampsia in high risk pregnant women is of prime importance. The omega-3 supplementation may reduce the risk of preeclampsia. Objective: The aim of the present study was to assess the effects of omega-3 supplementation on high risk pregnancy for preeclampsia in the city of Qazvin. Methods: This was a single-blind randomized clinical trial conducted on 100 high risk pregnant women for preeclampsia over a period between 14 to 18 weeks of gestation in the city of Qazvin, Iran. Fifty patients were assigned to omega-3 group and another 50 to placebo group. Women were given a daily supplementation of 1000mg omega-3 or placebo until delivery. Later, preeclampsia and pregnancy outcome were assessed in both groups. Data were analyzed statistically using t-test, chi square test, Mannwhitney, and Fisher exact tests. Findings: There were significant differences between the omega-3 and placebo groups regarding the rate (p=0.015) and intensity (p=0.01) of preeclampsia. Statistically, a significant correlation between the omega-3 group and outcome of pregnancy including the birth weight (p=0.000) and apgar score (p=0.002) was found. Conclusion: Our results suggest that supplementation with omega-3 during pregnancy reduces the risk of preeclampsia in high risk pregnant women. Thus it seems necessary to promote educational programs on nutrition for pregnant women.

Keywords

High Risk Pregnancy, Preeclampsia, Fatty Acids with Long Chains of Omega3

بارداری پرخطر، پره اکلامپسی، اسیدهای چرب با زنجیره طولانی(امگا 3)

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