Comparison of Hashimoto thyroiditis in patients with type 1 diabetes and controls

F Saffari; A Asgari; T Sadeghi; F hajmanocheri

Journal of Inflammatory Diseases

The Official Journal of Qazvin University of Medical Sciences

Current Issue All Issues In Press Accepted Manuscripts Search

Journal Information Editors & Boards Indexing and Listing Sources Journal Metrics Open Peer Review (OPR)Publication Ethics and Publication Malpractice Statement Reviewer and AE Registration Form Support Contact Us

Authors Guide Submit Manuscript

Comparison of Hashimoto thyroiditis in patients with type 1 diabetes and controls

Author(s):

F Saffari^1,*,

A Asgari¹,

T Sadeghi²,

F hajmanocheri¹

1Qazvin University of Medical Sciences, Qazvin, Iran

2TUMS, Tehran, Iran

Journal of Inflammatory Diseases:Vol. 15, issue 2; 86-93

Published online:Sep 30, 2011

Article type:Research Article

How to Cite:Saffari F, Asgari A, Sadeghi T, hajmanocheri F. Comparison of Hashimoto thyroiditis in patients with type 1 diabetes and controls. J Inflamm Dis. 2024;15(2):e155620. doi:

Abstract

Background: Type 1 diabetes is the most common metabolic disease worldwide. Thyroid autoimmune diseases is the most common endocrinopathy in diabetes type 1 .Therefore, assessment of thyroid function tests and anti thyroid antibodies in diabetic patients (type 1) is beneficial in early. Objective: The purpose of this study was to compare the anti-thyroid antibodies in diabetic children (type 1) with healthy children . Methods: In this descriptive-analytic study, 65 children with Type 1 diabetes and 65 healthy children who had referred to Children's Hospital in Qazvin were selected by simple sampling. Anti-TG, Anti-TPO, TSH and T4 were measured in both groups. Chi-square, t-independent and Kruskal Valis was used for statistical analysis. Findings: The difference between sex and age in both groups (case and control) was not significant but BMI percentile was significantly different. Positive Anti-TG was 10.8% in patients and was 1.5% in controls .The difference was statistically significant (p=0.029). 16.9% of patients and 3.1% of controls had positive Anti-TPO (p=0.024).10.8% of patients had increased TSH and decreased T4 level (Overt Hypothyroidism) .4.6% of controls had increased TSH and normal T4 level (Subclinical Hypothyroidism). The difference was statistically significant for T4. Conclusion: It seems that the prevalence of Hashimoto thyroiditis in patients with type 1 diabetes is more than healthy people. Hence, evaluation of thyroid function tests (TFT) and antithyroid antibodies (Anti-TPO) is necessary to diagnosis and treatment of autoimmune thyroid disorders.

Keywords

Type 1 diabetes

Hashimoto thyroiditis

anti-thyroid antibodies

Anti-TG

Anti TPO

Import into EndNote Import into BibTex

Share on

Comments

Number of Comments:0

Cited by

Scopus by DOI: 0
Last Update: 5 days ago
Scopus by Title: 0
Last Update: 5 days ago
Scopus by Title (Ref): 0
Last Update: 5 days ago
CrossRef: 0
Last Update: 6 days ago

Metrics

Ordering Reprints

Articles are published under the Creative Commons license stated on each article. No permission or royalty fee is required for uses permitted by that license. CCC handles optional bulk and customized reprint orders. Any quotation covers production and delivery services only, not copyright permission. > Request Reprints from CCC

Search Relations

Author(s):

F Saffari:[PubMed][Scholar]
A Asgari:[PubMed][Scholar]
T Sadeghi:[PubMed][Scholar]
F hajmanocheri:[PubMed][Scholar]

The Official Journal of Qazvin University of Medical Sciences

Outlines

Comparison of Hashimoto thyroiditis in patients with type 1 diabetes and controls

Abstract

Last Update: 5 days ago

Last Update: 5 days ago

Last Update: 5 days ago

Last Update: 6 days ago