Impact of disability and depression on quality of life in individuals with multiple sclerosis

authors:

avatar F Abbasi 1 , * , avatar AM Moosavi 1 , avatar H Mozhdehipanah 2

, Imam Khomeini International University, Qazvin,
Qazvin University of Medical Sciences, Qazvin, Iran

how to cite: Abbasi F, Moosavi A, Mozhdehipanah H. Impact of disability and depression on quality of life in individuals with multiple sclerosis. J Inflamm Dis. 2012;16(1):e155677. 

Abstract

  Background: Disability and depression are important predictors of reduced quality of life in individuals with Multiple Sclerosis (MS) .   Objective : This study was performed to assess the effect of disability and depression on the quality of life individuals with MS.   Methods: This was a comparative study, performed on 53 individuals with MS and a group of healthy individuals following age and sex adjustment in the city of Qazvin in 2009. These people were compared using the quality of life questionnaire (SF-36 ( , Expanded Disability Status Scale (EDSS), and the Beck Depression Inventory. Data were analyzed using t-test, linear regression and multivariate analysis.   Findings: Patients with MS had lower scores compared to the general population (healthy individuals) in subscale of the SF-36. The EDSS score was only predictive for physical functioning . Depression was significantly higher in those with MS than the healthy group (P<0.01).   Conclusion: Considering the e ffect of disability and depression on quality of life in patients with MS, the application of dual methods of medical and psychological treatment to improve the quality of life in patients with MS is recommended.