Frequency of Helicobacter pylori in paraffin embedded blocks of chronic tonsillitis patients (2008-2009)

AA Pahlevan; F Ahmadpour-Qazvini; T Naserpour Farivar; P Johari; F Safdarian; R Najafipour

Journal of Inflammatory Diseases

The Official Journal of Qazvin University of Medical Sciences

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Frequency of Helicobacter pylori in paraffin embedded blocks of chronic tonsillitis patients (2008-2009)

Author(s):

AA Pahlevan,

F Ahmadpour-Qazvini,

T Naserpour Farivar^1,*,

P Johari,

F Safdarian,

R Najafipour

1, Medical school, Qazvin University of Medical Sciences, Qazvin, Iran

Journal of Inflammatory Diseases:Vol. 16, issue 3; 19-25

Article type:Research Article

How to Cite:AA PahlevanF Ahmadpour-QazviniT Naserpour FarivarP JohariF SafdarianR Najafipouret al.Frequency of Helicobacter pylori in paraffin embedded blocks of chronic tonsillitis patients (2008-2009).J Inflamm Dis.16(3):e155705.

Abstract

Background: The presence of large number of tonsillectomy surgeries and also the possibility of tonsillar colonization by Helicobacter pylori as the causative agent of tonsillar hypertrophy make it necessary to investigate any possible correlation between the presence of this bacterium and the occurrence of tonsillar hypertrophy. Objective: To investigate the frequency of Helicobacter pylori in chronic tonsillitis patients. Methods: Scorpion real-time PCR was performed on 103 archived paraffin-embedded tonsillar samples collected from patients with tonsillar hypertrophy following tonsillectomy operation at ENT ward of Qods Hospital (Qazvin University of Medical Sciences), Qazvin (Iran) during 2008-2009. Findings: H. pylori DNA was present in 21.35% of total specimens. Conclusion: Although the existence of H. pylori in tonsillar tissue samples of patients with tonsillar hypertrophy is controversial however, it seems that the method by which the laboratory investigation is made may influence the results as the more sensitive and specific scorpion real-time PCR assay showed the tonsils could be considered as important reservoir of H. pylori.

Keywords

Tonsillar Hypertrophy, Helicobacter Pylori, Chronic Tonsillitis

هیپرتروفی لوزه، هلیکوباکتر پیلوری، التهاب مزمن لوزه

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