Association between class 1 integrons and multidrug resistance pattern among Enterobacter spp. isolated from Qazvin and Tehran teaching hospitals

Amir Peymani; Taghi Naserpour Farivar; P Ghoraiian; R Najafipour

Journal of Inflammatory Diseases

The Official Journal of Qazvin University of Medical Sciences

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Association between class 1 integrons and multidrug resistance pattern among Enterobacter spp. isolated from Qazvin and Tehran teaching hospitals

Author(s):

Amir Peymani¹,

Taghi Naserpour Farivar¹,

P Ghoraiian²,

R Najafipour^,*

1Cellular and Molecular Research Center, Qazvin University of Medical Sciences, Qazvin, Iran

2Qazvin University of Medical Sciences, Qazvin, Iran

Journal of Inflammatory Diseases:Vol. 18, issue 2; 30-38

Article type:Research Article

How to Cite:Amir PeymaniTaghi Naserpour FarivarP GhoraiianR NajafipourAssociation between class 1 integrons and multidrug resistance pattern among Enterobacter spp. isolated from Qazvin and Tehran teaching hospitals.J Inflamm Dis.18(2):e155827.

Abstract

Background: Multi-drug resistant (MDR) Enterobacter spp. containing class 1 integrons are considered as one of the major concerns of clinicians and infection control specialists . Objective: The aim of this study was to determine the association between class 1 integrons and the multidrug resistance pattern among Enterobacter spp . Methods: In this analytical study, antimicrobial susceptibility pattern were determined among 137 isolates of Enterobacter from Qazvin and Tehran hospitals during May 2011-September 2012. Then all isolates were screened for class 1 integrons using PCR assay. Data were analyzed using chi-square test and Fisher's exact test. Findings: The MDR pattern was found in 83 isolates (61%) and class 1 integrons were detected in 52 (63%) of these isolates. There was a significant association between the presence of class 1 integrons and the MDR pattern. Conclusion: With regards to the results, use of proper equipment for infection control and appropriate treatment strategies are necessary .

Keywords

Enterobacter

Integrons

Multiple Drug Resistance

Infection

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