Abstract
Background: Multi-drug resistant (MDR) Enterobacter spp. containing class 1 integrons are considered as one of the major concerns of clinicians and infection control specialists . Objective: The aim of this study was to determine the association between class 1 integrons and the multidrug resistance pattern among Enterobacter spp . Methods: In this analytical study, antimicrobial susceptibility pattern were determined among 137 isolates of Enterobacter from Qazvin and Tehran hospitals during May 2011-September 2012. Then all isolates were screened for class 1 integrons using PCR assay. Data were analyzed using chi-square test and Fisher's exact test. Findings: The MDR pattern was found in 83 isolates (61%) and class 1 integrons were detected in 52 (63%) of these isolates. There was a significant association between the presence of class 1 integrons and the MDR pattern. Conclusion: With regards to the results, use of proper equipment for infection control and appropriate treatment strategies are necessary .
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Copyright
© 2024, Journal of Inflammatory Diseases. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.