Association between class 1 integrons and multidrug resistance pattern among Enterobacter spp. isolated from Qazvin and Tehran teaching hospitals

authors:

avatar Amir Peymani 1 , avatar Taghi Naserpour Farivar 1 , avatar P Ghoraiian 2 , avatar R Najafipour , *

Cellular and Molecular Research Center, Qazvin University of Medical Sciences, Qazvin, Iran
Qazvin University of Medical Sciences, Qazvin, Iran

How To Cite Peymani A, Naserpour Farivar T, Ghoraiian P, Najafipour R. Association between class 1 integrons and multidrug resistance pattern among Enterobacter spp. isolated from Qazvin and Tehran teaching hospitals. J Inflamm Dis. 2014;18(2):e155827. 

Abstract

  Background: Multi-drug resistant (MDR) Enterobacter spp. containing class 1 integrons are considered as one of the major concerns of clinicians and infection control specialists .   Objective: The aim of this study was to determine the association between class 1 integrons and the multidrug resistance pattern among Enterobacter spp .   Methods: In this analytical study, antimicrobial susceptibility pattern were determined among 137 isolates of Enterobacter from Qazvin and Tehran hospitals during May 2011-September 2012. Then all isolates were screened for class 1 integrons using PCR assay. Data were analyzed using chi-square test and Fisher's exact test.   Findings: The MDR pattern was found in 83 isolates (61%) and class 1 integrons were detected in 52 (63%) of these isolates. There was a significant association between the presence of class 1 integrons and the MDR pattern.   Conclusion: With regards to the results, use of proper equipment for infection control and appropriate treatment strategies are necessary .