Abstract
Background: Because of the relationship between sesame oil consumption and reduced cardiovascular morbidity and mortality rate, research on dietary intake of sesame oil is necessary. Objective: The aim of this study was to determine the effects of dietary supplementation with virgin sesame oil (VSO) on lipid profile in rats. Methods: This experimental study was conducted in 28 adult male rats weighing 240-350 g. The experimental groups were fed with a diet supplemented with 0.25, 0.5 and 0.75 ml/kg/day VSO via gastric gavage for 30 days and the control group received saline. Serum levels of cholesterol, triglycerides, HDL and L DL were measured. Data were analyzed using one way ANOVA with LSD as post-hoc test. Findings: Serum cholesterol, triglycerides and LDL levels were significantly decreased in the experimental groups compared to the control group. HDL was increased in a dose dependent fashion, but the difference was statistically significant for the 0.5 and 0.75 ml/Kg/day groups compared to the control group. Conclusions: With regards to the results, virgin sesame oil supplementation decreased serum lipids that is probably due to the effects of antioxidants and unsaturated fatty acids .
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Copyright
© 2024, Journal of Inflammatory Diseases. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.