A comprehensive review of Zika virus infection

Ahmad Tavakoli; Maryam Esghaei; Mohammad Hadi Karbalaie Niya; Arezoo Marjani; Alireza Tabibzadeh; Mohammad Karimzadeh; Seyed Hamid Reza Monavari

Journal of Inflammatory Diseases

The Official Journal of Qazvin University of Medical Sciences

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A comprehensive review of Zika virus infection

Author(s):

Ahmad Tavakoli

¹,

Maryam Esghaei¹,

Mohammad Hadi Karbalaie Niya

²,

Arezoo Marjani¹,

Alireza Tabibzadeh¹,

Mohammad Karimzadeh¹,

Seyed Hamid Reza Monavari^1,*

1Department of Virology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran

2Research Center of Immunology, Institute of Immunology and Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran

Journal of Inflammatory Diseases:Vol. 22, issue 5; 87-105

Article type:Review Article

How to Cite:Ahmad TavakoliMaryam EsghaeiMohammad Hadi Karbalaie NiyaArezoo MarjaniAlireza TabibzadehMohammad KarimzadehSeyed Hamid Reza Monavariet al.A comprehensive review of Zika virus infection.J Inflamm Dis.22(5):e156117.

Abstract

Zika virus is a mosquito-borne flavivirus that is becoming a new global threat. Currently, serologic (ELISA) and molecular (RT-PCR) testing make the diagnosis of Zika virus infection. There is no specific drug available for Zika virus infection, and treatment is supportive based on reducing symptoms of disease. Protection against mosquito bites is the most effective way to prevent the infection. In this systematic review, all of the English published papers on Zika virus were assessed before December 2017, and were overviewed. Bibliographic databases had searched including; PubMed, Scopus, Google scholar, and Science Direct by using the keywords such as; “Zika virus”, “Zika fever”, and “Zika infection”. In this review, the pathogenesis, epidemiology, clinical features, transmission, laboratory diagnosis, treatment, and prevention of Zika virus infection were discussed.

Keywords

Zika virus infection

Mosquito vectors

Serologic test

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