Assessment the Relationship Between Phosphorus and Magnesium, Serum Level With Clinical Outcome in Head Trauma Patients

leili yekefallah; Sareh Mohammadi; Siyamak Yaghoubi; Maryam Mafi

Journal of Inflammatory Diseases

The Official Journal of Qazvin University of Medical Sciences

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Assessment the Relationship Between Phosphorus and Magnesium, Serum Level With Clinical Outcome in Head Trauma Patients

Author(s):

leili yekefallah

¹,

Sareh Mohammadi^2,*,

Siyamak Yaghoubi³,

Maryam Mafi³

1Department of Critical Care Nursing, Faculty of Nursing and Midwifery, Qazvin University of Medical Sciences, Qazvin, Iran.; Metabolic Diseases Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran.

2Department of Critical Care Nursing, Faculty of Nursing and Midwifery, Qazvin University of Medical Sciences, Qazvin, Iran.

3Department of Anesthesiology, Medical School, Qazvin University of Medical Sciences, Qazvin, Iran.

Journal of Inflammatory Diseases:Vol. 23, issue 5; e156185

Article type:Research Article

How to Cite:leili yekefallahSareh MohammadiSiyamak YaghoubiMaryam MafiAssessment the Relationship Between Phosphorus and Magnesium, Serum Level With Clinical Outcome in Head Trauma Patients.J Inflamm Dis.23(5):e156185.

Abstract

Background Traumatic brain injury is the second leading cause of death in Iran. Having knowledge of the factors affecting the clinical outcomes of these patients can improve the therapeutic outcomes.
Objective The aim of this study was to determine the relationship of phosphorus (P) and magnesium (Mg) serum levels during admission with clinical outcomes of patients with head trauma.
Methods This descriptive-analytic study was conducted in the intensive care unit of Shahid Rajaei Hospital in Qazvin, Iran from March to August 2018. Participants were 70 patients with head trauma under mechanical ventilation who had inclusion criteria. They were selected using a convenience sampling technique. Based on admission P level, patients were divided into two groups of hypophosphatemia (P> 3 mg/dL) and normophosphatemia (P≥3 mg/dL); and based on admission Mg level, they were assigned into two groups of hypomagnesemia (Mg <1.5 mg/dL) and normomagnesemia (Mg ≥1.5 mg/dL). Hypomagnesemia group was compared with normomagnesemia group, and hypophosphatemia group with normophosphatemia group in terms of clinical outcomes.
Findings There was a significant difference between two Mg groups in terms of successful weaning (P=0.03), mechanical ventilation duration (P=0.01), and death rate (P=0.03), but not in terms of endotracheal extubation and length of hospital stay (P>0.5). The difference between two P groups was significant only in terms of successful weaning (P=0.006).
Conclusion Serum levels of phosphorus and magnesium affect the clinical outcomes of patients with head trauma.

Keywords

Mechanical Ventilation

Head trauma

Hypophosphatemia

Hypomagnesemia

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