Dyschloremia During Severe COVID‑19 Infection in Intensive Care Unit Patients

marayam gheraati; Monirsadat Mirzadeh; fateme nazifi; Negar Davoodi; Atefeh Khoshkchali

Journal of Inflammatory Diseases

The Official Journal of Qazvin University of Medical Sciences

Current Issue All Issues In Press Accepted Manuscripts Search

Journal Information Editors & Boards Indexing and Listing Sources Reviewer and AE Registration Form Journal Metrics Open Peer Review (OPR)Publication Ethics and Publication Malpractice Statement Support Contact Us

Authors Guide Submit Manuscript

Dyschloremia During Severe COVID‑19 Infection in Intensive Care Unit Patients

Author(s):

marayam gheraati¹,

Monirsadat Mirzadeh

¹,

fateme nazifi²,

Negar Davoodi^1,*,

Atefeh Khoshkchali¹

1Metabolic Diseases Research Center, Research Institute for Prevention of Non-communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran.

2Department of Critical Care Nursing, Faculty of Nursing and Midwifery, Qazvin University of Medical Sciences, Qazvin, Iran.

Journal of Inflammatory Diseases:Vol. 26, issue 4; 201-208

Article type:Research Article

How to Cite:marayam gheraatiMonirsadat Mirzadehfateme nazifiNegar DavoodiAtefeh KhoshkchaliDyschloremia During Severe COVID‑19 Infection in Intensive Care Unit Patients.J Inflamm Dis.26(4):e156327.

Abstract

Background: Dyschloremia is one of the most prevalent abnormalities that is highly associated with a high level of mortality in intensive care unit (ICU) patients. The current study evaluated serum chloride levels in COVID-19 patients hospitalized in the ICU. Methods: This cross-sectional study was conducted on 245 patients with severe COVID-19 who were admitted to the intensive care unit (ICU). Electrolytes, albumin, liver function test, complete blood count, serum chloride, and VBG were among the laboratory markers compared. The Chi-square, t-test, and logistic regression models were used to examine the relationship between these markers and the key outcomes, which included severity, mortality, intubation, and hospitalization. Findings: The Mean±SD age of patients was 58.16±17 years. The mean serum chloride level in the studied patients was 109.6±5.1 with a range of 100-134. According to the regression logistic model, variables like age, intubation status, pH, and chlorine levels significantly affected the outcome of COVID-19 disease. Patients with acidosis were 4.7 times more likely to die than those with alkalosis (P

Keywords

Intensive care unit (ICU)

Mortality

comments