Multiple sclerosis (MS) is a chronic autoimmune disease, progressing in central nervous system that typically begins within the age range of 20 to 40 years. More females are diagnosed with MS than males (
1). This disease is the third most common cause of neurological disabilities (
2). According to the World Health Organization (WHO) report 2008, about 1.3 million people around the globe were diagnosed with MS (
3). This number is increasingly growing and from 2008 to 2013, the number increased from 30 to 33 per 100000 (
4). The rates of the prevalence of MS vary worldwide. Countries with higher number of diagnosis (more than 30 per 100000 people) are in north of Europe, Northern America, south of Canada, south of Australia, New Zealand, Iran, and Turkey, and the ones with lower rates (less than 5 per 100000) are countries in south of Europe, Japan, China, and Southern America (
5). Incidence of MS is particularly high in the north of Scotland (in Orkney Islands) (
6). The MS Association of Iran reported about 40000 patients with MS in the country (
7). The number of patients with MS is higher in Isfahan than the other parts of the country, and Isfahan with 4250 patients has the highest prevalence in the Iran (
8). Etemadifar et al. (
9), reported the number of patients with MS in Hamedan province 1100. Patients with MS have many physical and mental problems that limit the presence of patients in health promotion activities and increase the secondary complications and limitations in independent life, which ultimately have a negative impact on patient’s quality of life (
10).
Quality of life, with multiple measures such as physical, mental and social aspects, is used as an important indicator resulting from various researches regarding the health of the patients and effectiveness of the treatment process (
11).
Chronic diseases such as MS cause various physical challenges such as blue vision, diplopia, muscle weakness, balance and coordination problems, sensory and cognitive disturbances, pain (medium to intense), memory loss, inability to focus, fatigue, tremor, dizziness, bowel problems, bladder and sexual dysfunction (
8), swallowing and speech problem, impaired ability to regulate temperature (
12), and paralysis of the hands and feet (
6). A study by Lotfi et al., (cited by Agha Yousefi et al.) suggested sensory and vision disturbances as the most common symptoms among Iranian young adults with MS (
13).
In addition to physical challenges, MS could trigger various psychological and mental illnesses in the patients. More studies found that due to chronic and unpredictable nature of this disease, patients with MS are more liable to depression, stress, and anxiety than the other problems such as cognitive disturbances and extreme irritability from which anxiety, stress, and depression are the most common prevalent ones (
14,
15). About 48% of the patients are diagnosed with anxiety, stress, and depression within the first year of diagnosis (
16). Stress, by itself, can exacerbate other symptoms caused by MS. It could also threaten other aspects of the patient’s life and lead to divorce, loss of job, and other difficulties in patients’ relationships (
15). Depression in such patients could potentially lead to constant unhappiness, loss of hope for future, frequent mental images of disability, constant flow of negative thoughts, and in extreme cases, suicidal behavior (
17). All of these negatively affect the patients’ quality of life, which could discourage them to follow treatment process, hence worsening the symptoms (
18). The results of some studies showed that stress, anxiety, and depression symptoms in patients with MS were associated with relapse of the disease and a decrease in the quality of life of patients. In addition, having mental health can prevent the development of depression, anxiety, and stress in patients and, consequently, improve their quality of life and satisfaction (
19).
According to the many problems of patients with MS, many researchers try to study and develop interventions to control such problems. Due to the urgency of taking measures to control the debilitating problems and improving the patients’ quality of life, drug therapy alone has no effect on the quality of life of such patients (
20); therefore, other methods should be employed in addition to drug therapy. Today, many physicians recognize faith and spirituality as an important source of health and well-being; hence, they often know that they should consider patients' spiritual issues in the treatment process (
18). Spirituality involves self-perceptions and a combination of personality factors and fundamental beliefs about perceiving meaning in life that these beliefs correlate to various aspects of life including social, physical and mental aspects (
18). Spirituality is the aspect of human that shows the connection and unity with the universe and extends him beyond the limits of time and place and material interests (
21).
Spirituality along with religious forces leads to a positive attitude toward the world and helps the individual to accept irreplaceable situations such illness and the individual hopes to improve life (
22). They could build foundation for adaptability, hope, and healing for the patient. Spiritual treatment approaches encourage therapists to help the patients according to their religious beliefs and benefit from determinism to help patients (
18). In addition, better performance could be achieved if the techniques are implemented in a group. Interaction with other patients helps patients be more aware of own situation (
23).
Corey found that the following factors were important in the therapeutic progress:
1. Commonness: Patient does not see him/herself the only person with this disease.
2. Friendship: In a group, the patient perceives meaning when people in the group support each other.
3. Hope: Patients find hope when they see the other people that are at similar or worse conditions, can perceive a meaning in life, and have positive attitudes towards life (
24).
Today, along with spirituality, the important issue that attracted the attention of psychologists and mental health professionals over the past few decades is the importance of spiritual health in humans. Spiritual health is one of the important aspects of health and the core of health in humans (
25). Spiritual health is the only force that coordinates physical, mental, and social aspects of life and is necessary to adapt to the disease (
26). According to the WHO, the human health has four main aspects including physical, mental, social, and spiritual and spiritual health is the most crucial one for development (
27). Spiritual health has two aspects of religious health and existential health. Religious health is central to the quality and understanding of one's health from spiritual life, when it is linked with higher power, and existential health is related to the adaptation of individuals to society and themselves and to the social and mental concerns of individuals (
28). Individuals with a high spiritual health can adapt to their problems. When spiritual health comes at a serious risk, the person may have mental disorders such as loneliness, anxiety, and feeling of futility (
29).
The first research regarding the quality of life of people with MS was published in 1990. Many works are conducted ever since (
16). Haresabadi et al. (
1), reported in their study that the quality of life of patients with MS admitted to Ghaem Hospital, in Mashhad, was average. Heidari Sureshjani et al. (
8), found a lower than average score for the quality of life of patients with MS in Isfahan. Tepavcevic et al. (
29), and Bašić Kes et al. (
30), reported a lower quality of life for patients with MS patients compared with others. Allahbakhshian et al. (
31), showed a relationship between religious beliefs and spiritual health of patients with MS. Spiritual group treatment by Taghizade and Miralaee was very effective in females diagnosed with MS (
18). Dehghani et al. (
15), reported significantly high levels of stress, anxiety, and depression, which can endanger the health state. Mardani Valdani and Ghafari found in their study that various techniques such as logotherapy (increasing the responsibilities), transforming the patients’ beliefs towards life, and raising hope in life can help the patients with MS improve their quality of life both in physical and mental aspects (
32). Khodaveisi et al. (
20), showed that the Orem self-care-training model was beneficial in improving the quality of life of patients with MS. Beiske et al. (
33), showed that patients with MS exhibited 31.4% and 19.3% depression and stress symptoms, respectively. Therefore, it can be concluded that patients with MS exhibit depression and stress, twice and three times as much as the healthy people, respectively, in Norway. Ashjazade et al. (
4), showed that mental aspects of life in patients with MS were considerably lower than those of the healthy individuals. Nasiry Zarrin Ghabaee et al. (
34), reported that spiritual health and religious beliefs could play an important role in improving the quality of life of in patients with MS. Akbari and Hossaini showed in their study a non-linear relationship between spiritual health and the areas of quality of life and mental health (
35).
Nowadays, governments acknowledge that the improvement of quality of life is essential in socioeconomic development. Therefore, understanding the condition and quality of life features of patients with MS are crucial for intervention and treatment processes (
36). Since MS is the second cause of youth disability in Iran (
37), it is important to study the quality of life in patients with MS and the factors affecting it; also, studying the nonpharmacological interventions such as spiritual therapy, especially in group therapy, and using its results can help the therapists to deal with such patients. Unfortunately, there are not many studies on spiritual health and nonpharmacological intervention approaches in patients with MS. One of the specific features of the current study was simultaneous examination of group spirituality therapy on two aspects of quality of life and spiritual health of patients with MS.
As already mentioned, the current study aimed at investigating the effect of group spirituality therapy on quality of life of patients with MS in Ahvaz. The study hypotheses were as follows:
1. Group spirituality therapy improves the quality of life of patients with MS.
2. Group spirituality therapy improves the physical quality of life of patients with MS.
3. Group spirituality therapy improves the mental quality of life of patients with MS.
4. Group spirituality therapy improves the spiritual health of patients with MS.