Evaluation of standardized ginseng extract Panax (G115 ®) effect on fasting blood glucose levels, glycated hemoglobin and lipid profile in patients with diabetes type 2

Seyed Ahmad Hosseini; Ali Ehsanpour; Mehdi Asgari; Reza Malihi

Jundishapur Journal of Chronic Disease Care

The Official Journal of Ahvaz Jundishapur University of Medical Sciences

Current Issue All Issues In Press Accepted Manuscripts Search

Journal Information Editors & Boards Indexing and Listing Sources Journal Metrics Open Peer Review (OPR)Publication Ethics and Malpractice Statement Contact Us Reviewer and AE Registration Form Support

APC

Authors Guide Submit Manuscript

Evaluation of standardized ginseng extract Panax (G115 ®) effect on fasting blood glucose levels, glycated hemoglobin and lipid profile in patients with diabetes type 2

Author(s):

Seyed Ahmad Hosseini¹,

Ali Ehsanpour²,

Mehdi Asgari³,

Reza Malihi^1,*

1Department of Nutrition, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

2Department of Internal Medicine, Razi Hospital, Ahvaz Jundishpur University of Medical Sciences, Ahvaz, Iran

3Department of Surgery, Razi Hospital, Ahvaz Jundishpur University of Medical Sciences, Ahvaz, Iran

Jundishapur Journal of Chronic Disease Care:Vol. 2, issue 3; e93793

Published online:Jul 30, 2013

Article type:Research Article

Received:May 15, 2019

Accepted:Jan 11, 2013

How to Cite:Seyed Ahmad HosseiniAli EhsanpourMehdi AsgariReza MalihiEvaluation of standardized ginseng extract Panax (G115 ®) effect on fasting blood glucose levels, glycated hemoglobin and lipid profile in patients with diabetes type 2.Jundishapur J Chronic Dis Care.2(3):e93793.

Abstract

Introduction: Despite enormous efforts to search for cure, diabetes mellitus still remains as a formidable challenge for public health. This project was designed to evaluate effect of standardized ginseng extract Panaxs (G115®) on fasting blood glucose levels, glycated hemoglobin and lipid profiles in patients with diabetes type 2.

Materials & Methods: In this randomized, double blind placebo controlled clinical trial, 30 patients with type 2 diabetes were contributed. They were divided into two groups (n=15 each), the randomized and placebo groups, the former received300 mg/day G115 and placebo received300 mg/d wheat flour. FBS, HbA1c and lipid profile were determined at baseline and at the end of study. SPSS version 18.0 (SPSS Inc, Chicago, IL, USA) was used for data analysis. Independent and paired samples T-test was applied for comparison.

Results: Subjects randomized to G115, as compared to the placebo group, had a significant decrease in HbA1c (t= -2.593,p=0.015)) and FBS levels (t=-2.13,p=0.042). There was no improvement lipid profiles of subjects randomized to G115, compared to controls.

Conclusion: Results of this study suggest that G115 supplementation in subjects with type 2 diabetes may improve glucose control but it has no significantly effect on lipid profiles.

Keywords

Panax ginseng

Fasting blood glucose

Glycated hemoglobin

Lipid profiles

References

1.
The references are available in PDF file.

comments