Long-term follow-up for the results of the treatment with Anti-Thyroid Drugs, Radioactive iodine and surgery in patients with Graves, disease

Keywords

In a retrospective study 580 patients with Graves disease were evaluated. They were treated with one of the treatment methods from October 1999 until September 2005. Using a questionnaire that related data were collected: demographic information onset of disease the recurrence rate incidence of hyperthyroidism and side effects of treatment were collected. Out of 580 patients enrolled the study 268 (46%) were treated with anti-thyroid drugs (for 18 months at least) 284 (49%) with radioactive iodine and 28 (5%) underwent the surgery. Recurrence rates of hyperthyroidism after treatment with anti-thyroid drugs iodine therapy and surgery were recorded at 53% 8% 14% respectively (P< 0/001). Hypothyroidism occurence after three methods was 6% 74% and 71% respectively. Overall