Background:
When a primary radiation interacts with a medium, the secondary radiations are produced, that the contribution of these secondary radiation should considered in the calculation of dose. Build-up factor is a dosimetric correction factor to assume effect of secondary radiation in calculation of dose. Calculation of this factor is very difficult and time consuming. Due to significance of this factor and difficulties in calculation of this factor in other method, the aim of this study is to calculate Build-up factor of cobalt-60 by using of Tissue Air Ratio concept in water