Receiver operating characteristic curve's application and interpretation in medical research

Authors

Mojtaba Sepandi1, Hamid Heidarian Miri1, Abdolreza Rajaeefard2,*
1PhD student of Epidemiology, Department of Epidemiology, Faculty of Health, Shiraz University of Medical Sciences, Shiraz, Iran
2Professor of Biostatistics, Department of Epidemiology, Faculty of Health, Shiraz University of Medical Sciences, Shiraz, Iran
*Corresponding Author: Professor of Biostatistics, Department of Epidemiology, Faculty of Health, Shiraz University of Medical Sciences, Shiraz, Iran Email: [email protected]

Jentashapir Journal of Cellular and Molecular Biology:Vol. 1, issue 1; e94039
Published online:Mar 30, 2010
Article type:Research Article
Received:May 19, 2019
Accepted:Mar 30, 2010
How to Cite:Sepandi M, Heidarian Miri H, Rajaeefard A. Receiver operating characteristic curve's application and interpretation in medical research. Jentashapir J Cell Mol Biol. 2010;1(1):e94039. doi:

Abstract

Receiver operating characteristic(ROC), a sensitive diagnostic test that Plots ssensitivity in the y-axis and the rate of false positives in the x-axis, is prepared to be a useful method for evaluating the performance of the diagnostic test. The aim of this study was to introduce the ROC analysis in a nonmathematical and non-statistical way. Important concepts that are needed to use and to interpret this type of analysis correctly include quantitative and qualitative diagnostic tests, sensitivity and specificity, area under the curve, and 95 % confidence intervals. Finally, the ROC analysis software has also been discussed in brief.

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Copyright

© 2010, Jentashapir Journal of Cellular and Molecular Biology. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.

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