The house-fly, Musca domestica L., not only is a nuisance pest, but also acts as an important mechanical vector for lots of pathogenic microorganism agents, including: bacteria, protozoa, worms, fungi and viruses amongst humans and animals. The aim of this study was to isolate and identification bacteria that are pick up by house-fly over the human and animal premises. In this study totally 230 houseflies were collected to isolate their bacteria, from the central slaughter house and a zoo in Ahvaz SW Iran. The most common isolated bacteria were Escherichia coli with 230 cases (36.5%). The results of the current study confirm that flies are much more than a nuisance and that they pose potentially serious health risks. Consequently, the population of houseflies has to be controlled.
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