Antimycobacterial activity of partial purified extract of Allium ascalonicum

Mansour Amin; Sepideh Segatoleslami; Mohammad Hashemzadeh

Jundishapur Journal of Microbiology

Ahvaz Jundishapur University of Medical Sciences

Current Issue All Issues In Press Accepted Manuscripts Search

Editors & Boards Journal Information Indexing and Listing Sources Journal Metrics Open Peer Review (OPR)Publication Ethics and Malpractice Statement Reviewer and AE Registration Form Contact Us Support

APC

Authors Guide Submit Manuscript

Antimycobacterial activity of partial purified extract of Allium ascalonicum

Author(s):

Mansour Amin^1,*,

Sepideh Segatoleslami²,

Mohammad Hashemzadeh²,

1Infectious and Tropical Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences-Department of Medical Microbiology, Ahvaz Jundishapur University of Medical Sciences, mnsamin@yahoo.com, Iran

2Department of Medical Microbiology, Ahvaz Jundishapur University of Medical Sciences, Iran

Jundishapur Journal of Microbiology:Vol. 2, issue 4; 144-147

Article type:Research Article

Received:Jun 01, 2009

Accepted:Nov 01, 2009

How to Cite:Mansour AminSepideh SegatoleslamiMohammad Hashemzadeh Antimycobacterial activity of partial purified extract of Allium ascalonicum.Jundishapur J Microbiol.2(4):144-147.

Abstract

Introduction and objective: The World Health Organization estimates that about 8 to 10 million new Tuberculosis (TB) cases occur annually worldwide and its incidence is currently increasing. There are two million deaths from TB each year. The plants are an important source of new antimicrobial agents. In this study, antibacterial activity of Allium ascalonicum against Mycobacterium tuberculosis was evaluated.

Materials and methods: To extraction antibacterial agent from this plant, 100g of underground root of A. ascalonicum was mixed with 100ml ethyl acetate and shacked gently. Partially purified antibacterial compound was isolated by organic solvents. Antibacterial activity of this fraction against M. tuberculosis was performed using the E test.

Results: Shallot extract showed antimycobacterial activity with a minimum inhibitory concentration (MIC) value of 500μg/ml.

Conclusion: It is implied that A. ascalonicum extract could be used as an effective antibacterial agent against M. tuberculosis, which is a resistant infection in pulmonary tuberculosis.

Keywords

Antibacterial effect

Allium ascalonicum

Mycobacterium tuberculosis

Full Text

Full text is available in PDF

comments