Background:Chlorhexidine gluconate (CHX) is the most common antimicrobial agent used against oral pathogens, however information on its ability to inhibit and disrupt anaerobic single and multispecies biofilms is relatively unknown.
Objectives:The purpose of this study was to test the efficacy of CHX for its biofilm inhibition and disruption properties using crystal violet assay.
Materials and Methods:Biofilm assays were carried out on single and multispecies of four oral pathogens:
Results:Streptococcus mutans, Fusobacterium nucleatum and multi-species biofilm formation were inhibited in more than 90% of cases at concentrations of 3-12 mg/L. CHX exhibited strong disruptive activity (> 65%) on one-day old biofilms of
Conclusions:In conclusion, CHX was a high effective biofilm inhibitor on
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