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The Study of Mycobacterium tuberculosis in Iranian Patients With Lung Cancer

Author(s):
Amir Mohamad Hashem AsnaashariAmir Mohamad Hashem Asnaashari1, Ali SadrizadehAli Sadrizadeh2, Hamid AhmadiHamid Ahmadi3, Mojtaba MeshkatMojtaba Meshkat4, Aida GholoobiAida Gholoobi5, Fariba Rezai TalabFariba Rezai Talab6, Mahnaz AaminiMahnaz Aamini6, Sayed Hosain Ahmadi HosainiSayed Hosain Ahmadi Hosaini6, Davoud AttaranDavoud Attaran1, Mohammad TohidiMohammad Tohidi1, Shahrzad Mohammadzadeh LariShahrzad Mohammadzadeh Lari1, Reza BasiriReza Basiri1, Maryam sadat NabaviniaMaryam sadat Nabavinia5, Sina RostamiSina Rostami7, Zahra MeshkatZahra MeshkatZahra Meshkat ORCID8,*
1Department of Pulmonary Diseases, Ghaem hospital, Mashhad University of Medical Sciences, IR Iran
2Department of Thoracic Surgery, Ghaem hospital, Mashhad University of Medical Sciences, Mashhad, IR Iran
3School of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran
4Isalmic Azad University, Mashhad Branch, Mashhad, IR Iran
5Microbiology and Virology Research Center, Mashhad University of Medical Sciences, Mashhad, IR Iran
6Department of Pulmonary Diseases, Imam Reza hospital, Mashhad University of Medical Sciences, IR Iran
7School of Sciences, Ferdowsi University of Mashhad, Mashhad, IR Iran
8Womens Health Research Centre, Mashhad University of Medical Sciences, Mashhad, IR Iran


Jundishapur Journal of Microbiology:Vol. 6, issue 3; 237-41
Published online:Apr 30, 2013
Article type:Research Article
Received:Mar 26, 2012
Accepted:Jul 02, 2012
How to Cite:Amir Mohamad Hashem AsnaashariAli SadrizadehHamid AhmadiMojtaba MeshkatAida GholoobiFariba Rezai TalabMahnaz AaminiSayed Hosain Ahmadi HosainiDavoud AttaranMohammad TohidiShahrzad Mohammadzadeh LariReza BasiriMaryam sadat NabaviniaSina RostamiZahra Meshkatet al.The Study of Mycobacterium tuberculosis in Iranian Patients With Lung Cancer.Jundishapur J Microbiol.6(3):237-41.https://doi.org/10.5812/jjm.4993.

Abstract

Background:

Mycobacterium tuberculosis has the ability to invade type II alveolar epithelial cells. As a result, the associations between invasion of alveolar epithelial cells and pathogenesis of lung infection seem strong.

Objectives:

The current study aimed to evaluate the presence of M. tuberculosis in patients with lung cancer.

Patients and Methods:

This cross-sectional study was performed on samples collected from 380 patients with lung cancer who referred to two state-run hospitals in Mashhad, Iran. Microscopic and cultural methods were utilized to assess the presence of M. tuberculosis in the patients` specimens.

Results:

The subjects included 252 (66.3%) males and 128 (33.7%) females. Based on cultural and microscopic methods, M. tuberculosis infection was observed in twenty six (6.8%) of cases.

Conclusions:

Results of the current study showed the high prevalence of M. tuberculosis among the patients with lung cancer; therefore, it seems that continuous surveillance is essential to monitor the M. tuberculosis in the patients with lung cancer.

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