Antioxidant and Antibacterial Properties of Methanolic Extract of Green Seaweed Chaetomorpha linum From Gulf of Mannar: Southeast Coast of India

1Molecular Diagnosis and Drug Discovery Laboratory, Department of Biotechnology, School of Life Sciences, Karpagam University, Coimbatore, Tamilnadu, India

Jundishapur Journal of Microbiology:Vol. 5, issue 2; 411-415

Published online:Apr 30, 2012

Article type:Research Article

Received:May 15, 2011

Accepted:Nov 02, 2011

How to Cite:Palanisamy SenthilkumarSellappa SudhaAntioxidant and Antibacterial Properties of Methanolic Extract of Green Seaweed Chaetomorpha linum From Gulf of Mannar: Southeast Coast of India.Jundishapur J Microbiol.2012;5(2):411-415.https://doi.org/10.5812/jjm.3400.

Abstract

Background: Plants are an essential and integral part of complementary and alternative medicine due to their ability to generate secondary metabolites that are used to restore health and treat many diseases.
Objectives: The aim of the present study was to determine the antioxidant and antibacterial activities of the green seaweed Chaetomorpha linum.
Materials and Methods: The antioxidant and antimicrobial activities of C. linum from the Mandapam coastal region of the Gulf of Mannar, on the southeast coast of India, were examined based on the free radical-scavenging activity of the 1, 1-diphenyl-2-picrylhydrazyl radical (DPPH), ferrous reducing antioxidant property (FRAP), and total phenolic content in the methanolic extract. The antibacterial properties of the methanolic extract of C. linum were tested against pathogenic bacterial strains, including Staphylococcus aureus, Bacillus cereus, Escherichia coli, Proteus mirabilis, Klebseilla pneumoniae, and Salmonella typhimurium, by cup-plate agar diffusion method.
Results: The DPPH scavenging activity was equivalent to an IC 50 value of 9.8 µg/mL ascorbic acid. The total phenolic content was 672.3 mg/g gallic acid equivalent, and the IC 50 value by FRAP assay was 8.2 µg/mL. The C. linum extract showed significant activity against the majority of bacteria, comparable with standard antibiotics.
Conclusions: C. linum has potential as a natural antioxidant and a natural source of antimicrobials against many microbes.

Keywords

Chaetomorpha linum

Antioxidant

Antibacterial Agents

Fulltext

Full text is available in PDF

comments

Crossmark

Checking

Share on

Comments

Number of Comments:0

Cited by

Metrics

Get Permission (article level)

Purchasing Reprints

Copyright Clearance Center (CCC) handles bulk orders for article reprints for Brieflands. To place an order for reprints, please click here ( https://www.copyright.com/landing/reprintsinquiryform/ ). Clicking this link will bring you to a CCC request form where you can provide the details of your order. Once complete, please click the ‘Submit Request’ button and CCC’s Reprints Services team will generate a quote for your review.

Search Relations

Author(s):

Palanisamy Senthilkumar:[PubMed][Scholar]
Sellappa Sudha:[PubMed][Scholar]