Relative Frequency of Sapovirus Among Children Under 5 Years of Age With Acute Gastroenteritis at the Aboozar Hospital, Ahvaz, Iran

1Department of Medical Microbiology, School of Medicine and infectious and Tropical Disease Research Center, Ahvaz Jundishapur University of Medical Science, Ahvaz, IR Iran

2Departments of Pediatrics, Ahvaz Aboozar Hospital, Ahvaz,IR Iran

Jundishapur Journal of Microbiology:Vol. 5, issue 1; 359-361

Published online:Apr 30, 2012

Article type:Research Article

Received:Dec 01, 2010

Accepted:Jun 01, 2011

How to Cite:Mehdi Parsa-Nahad, Ali Reza Samarbaf-Zadeh, Manoochehr Makvandi, Seyed Hamid Reza Mozhgani, Shahram Jalilian, et al. Relative Frequency of Sapovirus Among Children Under 5 Years of Age With Acute Gastroenteritis at the Aboozar Hospital, Ahvaz, Iran.Jundishapur J Microbiol.2012;5(1):359-361.https://doi.org/10.5812/kowsar.20083645.2371.

Abstract

Background: Gastroenteritis is a common cause of morbidity and mortality in humans all over the world, especially in infants under 5 years of age. Many microorganisms, including viruses, have been identified as the causative agents of gastroenteritis. Sapovirus is a major causative agent of acute viral diarrhea that occurs mostly in children under 5 years of age.
Objectives: The aim of this study was to determine the prevalence of Sapovirus infection among children under 5 years of age who had gastroenteritis and were referred to Aboozar Hospital, Ahvaz, Iran. Patients and Methods: All fecal specimens were collected from children with acute gastroenteritis, Sapovirus RNA was extracted using TRIzol and detected by reverse transcriptasepolymerase chain reaction (RT-PCR) followed by sequencing of the positive samples.
Results: Of the 200 clinical stool samples collected, 6 (3%; 5 samples from male patients and 1 from a female patient) were found to be positive for Sapovirus by the RT-PCR method. The identityof t PCR products was confirmed by sequencing. Sapoviruses belonging to genogroup II were identified as the dominant type causing gastroenteritis in children. The incidence of Sapovirus infection was the highest during the coldest months.
Conclusions: Sapovirus prevalence in children under the age of 5 years with acute gastroenteritis was 3%, and genogroup II was the dominant type.

Keywords

Fulltext

Full text is available in PDF

comments

Crossmark

Checking

Share on

Comments

Number of Comments:0

Cited by

Metrics

Get Permission (article level)

Purchasing Reprints

Copyright Clearance Center (CCC) handles bulk orders for article reprints for Brieflands. To place an order for reprints, please click here ( https://www.copyright.com/landing/reprintsinquiryform/ ). Clicking this link will bring you to a CCC request form where you can provide the details of your order. Once complete, please click the ‘Submit Request’ button and CCC’s Reprints Services team will generate a quote for your review.

Search Relations

Author(s):

Mehdi Parsa-Nahad:[PubMed][Scholar]
Ali Reza Samarbaf-Zadeh:[PubMed][Scholar]
Manoochehr Makvandi:[PubMed][Scholar]
Seyed Hamid Reza Mozhgani:[PubMed][Scholar]
Shahram Jalilian:[PubMed][Scholar]
Roya Pirmoradi:[PubMed][Scholar]
Ahmad Shamsi-Zadeh:[PubMed][Scholar]