Abstract
Subjects and Methods: This review underlines the nephroprotective effect of trimetazidine on kidney injury models. For this review, the articles have been searched in the databases, including PubMed, Scopus, Web of science, and Google Scholar. The search process was provided using these keywords: “Trimetazidine”, “kidney”, “nephrotoxicity”, “renal ischemia – reperfusion injury”, and “Protective.”
Results: Present study validates which trimetazidine as a potential agent alleviates kidney dysfunction in experimental models through several mechanisms.
Conclusion: Trimetazidine could be considered as promising candidate to treat a variety of kidney diseases in the future.