Comparison of cytological parameters of exfoliated buccal mucosal cells in different temperament groups

How to Cite:Zendehboodi Z. Comparison of cytological parameters of exfoliated buccal mucosal cells in different temperament groups.J Kermanshah Univ Med Sci.2017;21(1):e69515.https://doi.org/10.22110/jkums.v21i1.3286.

Abstract

Introduction: Temperament (Mizaj) forms the basic concept of Iranian traditional medicine (ITM), and greatly influences the diagnosis and treatment of diseases, as well as maintains the ideal healthy state of an individual. In particular, temperament is presumed to affect the morphological, physiological, and psychological features of a person; however, its influence on biological features remains unclear in practical ITM. This study aimed to evaluate the association between the temperament and the cytological features of buccal mucosa in healthy people.

Methods: The study sample included 75 healthy individuals from Fars province, southern Iran. The temperament was determined using a self-reported temperament identification scale. Based on the questionnaire, volunteers were classified in nine temperaments including one equilibrium, four simple temperaments (warm, cold, moist, and dry,) and four combined temperaments (warm–moist, warm–dry, cold–moist, cold–dry). Smears collected from the buccal mucosa of participants were analyzed for biomarkers of DNA damage, cytokinetic defects, proliferative potential, and cell death using micronucleus (MN) assay. Student’s t-test or Mann–Whitney U test was applied to identify the differences between groups.

Results: DNA damage (nuclear buds) and cell death biomarkers (condensed chromatin, karyorrhexic, pyknotic, and karyolitic cells) reported significant differences between certain temperament groups.

Conclusions: The present study reported that the aforementioned cytological parameters could be affected by the temperament; however, more studies with greater sample sizes are warranted.

Keywords

temperament

buccal cells

micronucleus test

cytological parameters

Fulltext

The full text of this article is available on PDF

References

1.
The refrences of this article is available on PDF.

comments

Crossmark

Checking

Share on

Comments

Number of Comments:0

Cited by

CrossRef 0

Metrics

Get Permission (article level)

Purchasing Reprints

Copyright Clearance Center (CCC) handles bulk orders for article reprints for Brieflands. To place an order for reprints, please click here ( https://www.copyright.com/landing/reprintsinquiryform/ ). Clicking this link will bring you to a CCC request form where you can provide the details of your order. Once complete, please click the ‘Submit Request’ button and CCC’s Reprints Services team will generate a quote for your review.

Search Relations

Author(s):

Zahra Zendehboodi:[PubMed][Scholar]