The relationship between oral lichen planus and gastrointestinal symptoms

1Dept. of Oral and Maxillofacial Diseases, Islamic Azad university, Dental branch, Tehran, Iran. Member of Craniomaxillofacial research center, Tehran Dental branch,, Islamic Azad university, Tehran, Iran

2Dept. of Oral and Maxillofacial disease, Islamic Azad University, Dental branch ,Tehran, Iran

3Dept. of Skin disease, Tehran University of Medical Sciences, Tehran, Iran

4Dept. of Gastrointestinal Diseases, Tehran University of Medical Sciences, Tehran, Iran

5Dept. of General Dentistry, Tehran Islamic Azad University, Tehran, Iran

Journal of Kermanshah University of Medical Sciences:Vol. 19, issue 7; e69756

Published online:Mar 19, 2016

Article type:Research Article

Received:Aug 22, 2015

Accepted:Jan 26, 2016

How to Cite:Mandana KhatibiSareh KhalifehHasan SeirafiMasoud Dooghaee Moghadam Atena Akhavan ModaresThe relationship between oral lichen planus and gastrointestinal symptoms.J Kermanshah Univ Med Sci.19(7):e69756.https://doi.org/10.22110/jkums.v19i7.2493.

Abstract

Background: Gastrointestinal complications, followed by involvement of gastrointestinal tract with oral lichen planus, are one of the problems of the patients with oral lichen planus. Gastrointestinal symptoms should be evaluated to reject malignancy probability (1-5%). Given lack of information and different reported frequencies in Iran and other countries, this study was conducted in order to evaluate the relationship between oral lichen planus and gastrointestinal symptoms in Razi hospital in Tehran.

Methods: This case-control study was performed on 50 patients with oral lichen planus and 50 controls by observation, clinical examination and biopsy, if necessary. Both groups were similar in sex, age, smoking, alcohol abuse and lack of systemic diseases. Gastrointestinal (GI) symptoms such as dysphagia, odynophagia, hunger pain, heartburn, flatus, etc. Were evaluated. Data were analyzed by SPSS statistical software using chi–square, Exact Fisher and T-student tests.

Results: Of 50 cases (OLP), 32(64%) patients and among 50 controls, 16 (32%) patients were found to have GI symptoms. Hunger pain (18%) and heartburn (18%) were the most common symptoms. Also, there was a significant difference in the prevalence of gastrointestinal symptoms between the two groups (P<0.005),

Conclusion: Gastrointestinal complications can be a part of mifestations of lichen planus and OLP. Knowledge of gastrointestinal symptoms in OLP patients can be helpful in preventing the G.I tract obstruction and malignancy by on time treatment.

Keywords

Oral lichen planus (OLP)

Gastrointestinal (GI )symptoms

esophageal obstruction

Fulltext

References

1.
The references of this article is available on PDF.

comments

Crossmark

Checking

Share on

Comments

Number of Comments:0

Cited by

CrossRef 0

Metrics

Get Permission (article level)

Purchasing Reprints

Copyright Clearance Center (CCC) handles bulk orders for article reprints for Brieflands. To place an order for reprints, please click here ( https://www.copyright.com/landing/reprintsinquiryform/ ). Clicking this link will bring you to a CCC request form where you can provide the details of your order. Once complete, please click the ‘Submit Request’ button and CCC’s Reprints Services team will generate a quote for your review.

Search Relations

Author(s):

Mandana Khatibi:[PubMed][Scholar]
Sareh Khalifeh:[PubMed][Scholar]
Hasan Seirafi:[PubMed][Scholar]
Masoud Dooghaee Moghadam :[PubMed][Scholar]
Atena Akhavan Modares:[PubMed][Scholar]