Portal vein thrombosis in pregnancy caused by hepatocellular carcinoma: A rare case report


avatar Nasrin Jalilian 1 , avatar Elham Shobeiri 2 , avatar Haleh Shahlazadeh 1 , *

Dept. of Obstetrics and Gynaecology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
Dept. of Radiology, School of Medicine, Kermanshah University of medical Sciences, Kermanshah, Iran

how to cite: Jalilian N, Shobeiri E, Shahlazadeh H. Portal vein thrombosis in pregnancy caused by hepatocellular carcinoma: A rare case report. J Kermanshah Univ Med Sci. 2014;17(12):e74286. doi: 10.22110/jkums.v17i12.1188.


Background: Portal Vein Thrombosis (PVT) during pregnancy is very rare. Its most common underlying causes are myeloproliferative disorders, pancreatitis, hepatocellular carcinoma and hereditary deficiency of natural anticoagulants (thrombophilia). Hepatocellular Carcinoma (HCC) is one of the most common gastrointestinal malignancies which is caused by toxins, alcohol and hepatitis viruses. Viral hepatitis is the cause of one-third of this carcinoma in China and Asia.
Case Report: We reported a case of Portal Vein Thrombosis (PVT) in a 31-year-old pregnant woman with an otherwise normal liver function, no risk factors, no hepatitis and no history of thrombophilia. Report of ultrasonography, CT scan and elevated alpha-fetoprotein test, indicated hepatocellular carcinoma and metastases was found in the bone and lungs.
Conclusion: This case is very rare in pregnancy so diagnosis and decision to termination of pregnancy is important.



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