The prevalence of congenital hypothyroidism in Kermanshah in 2006-2010

authors:

avatar Keyghobad Ghadiri 1 , avatar Mitra Darbandi 2 , * , avatar Lida Khodadadi 2 , avatar Nahid Khademi 3 , avatar Mehr Ali Rahimi 4 , avatar Mohammad Heidari 5 , avatar Keyvan Khassi 3

Infectious Disease Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran
Dept. of Public Health, School of Health, Kermanshah University of Medical Sciences, Kermanshah, Iran
Disease Department, Kermanshah Health Center, Kermanshah University of Medical Sciences, Kermanshah, Iran
Dept. of Internal Medicine, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
Dept. of Epidemiology, School of Health, Kerman University of Medical Science, Kerman, Iran
Journal of Kermanshah University of Medical Sciences: Vol.16, issue 7; e77296
published online: February 27, 2018
article type: Research Article
received: January 02, 2012
accepted: June 05, 2012

how to cite: Ghadiri K, Darbandi M, Khodadadi L, Khademi N, Rahimi M A, et al. The prevalence of congenital hypothyroidism in Kermanshah in 2006-2010. J Kermanshah Univ Med Sci. 2013;16(7):e77296. 

Abstract

Background: Congenital hypothyroidism (CH) is one of the most important causes of mental retardation in children and only if diagnosed early, its complications can be prevented. The worldwide incidence of congenital hypothyroidism is one in 3000-4000 live births but 2.2/1000 in Iran.  The aim of this study was to determine the incidence of congenital hypothyroidism in Kermanshah during 2006-2010.
Methods: This was a descriptive–analytical study. All infants that were born in Kermanshah city from 2006 to 2010 were studied. On days 3-5 after birth blood sampled were obtained from their heel and the samples were referred to the Health Center .The concentration of TSH was determined by filter paper, using ELISA method. Data were collected via recorded information in Kermanshah City Health Center and focal hypothyroid physician.
Results: 68587 infants were screened with 97% screening rate. The recall rate was 6/3percent.116 children were treated of which 65(56%) of them were males and 51(44%) were female. 28.4 percent of them had positive consanguineous marriage. There was statistically significant correlation between the TSH level and consanguineous marriage. The incidence of CH was 169 per 100000 live birth.
Conclusion: Because the incidence of CH is higher than that of the global rates, continuation and strengthening of newborn screening programs should be considered as a health priority.

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