The effects of one vs. two exhaustive sessions exercise on Cortisol, TNF-α and Adenosine Deaminase enzyme in endurance runners

authors:

avatar Daruish Sheikholeslami-vatani 1 , * , avatar Eidi Alijani 2 , avatar Behnam Boubani 2 , avatar Mohammad Abdi 3

Dept. of Physical Education and Sport Sciences, University of Kurdistan, Sanandaj, Iran
Dept. of Exercise Physiology, Islamic Azad University, Karaj Branch, Karaj, Iran
Dept. of Laboratory Sciences, Kurdistan University of Medical Sciences, Sanandaj, Iran
Journal of Kermanshah University of Medical Sciences: Vol.16, issue 2; e78823
published online: July 29, 2012
article type: Research Article
received: June 14, 2011
accepted: November 22, 2011

how to cite: Sheikholeslami-vatani D, Alijani E, Boubani B, Abdi M. The effects of one vs. two exhaustive sessions exercise on Cortisol, TNF-α and Adenosine Deaminase enzyme in endurance runners. J Kermanshah Univ Med Sci. 2012;16(2):e78823. 

Abstract

Background:  The purpose of the present study was to examine whether a first bout of exhaustive exercise can change inflammo-endocrine responses to second subsequent similar exercise on the same day.  Cortisol, TNF-α, and Adenosin Deaminas Enzyme (ADA) were assessed during a progressive endurance protocol.
Methods: Eight well trained endurance runners (aged 23.13±3.39 years; weight, 66.21±9.47 kg; Height 175.29±10.12 cm, and BMI 21.4±1.54 kg/m²), participated in a design with three following trials: 1) control condition day (rest)(C); 2) one bout of exhaustive exercise on a day (between the hours of 15.30-17)(E1); and 3) two bouts of exhaustive exercise on a day with 4 h rest between them (between the hours of 10-11.30 and again 15.30-17)(E2). Blood samples were drawn before exercise, immediately after exercise and 4 h post exercise from anterior median cubital vein.
Results: The results of the present study, using two way repeated ANOVA, showed that salivary Cortisol increased significantly, in both E1 and E2 situations (p<0.05). In this respect, there was no difference between exercise (E1 and E2) with respect to control condition. Exercise-induced increase of TNF-α was only significant during two bouts of exhaustive exercise on a day (E2) (p<0.05). The ADA enzyme activity did not alter in various conditions.
Conclusion: Increasing aerobic exhaustive exercise sessions in a day can enhance the amount of inflammation, though; these alterations are not caused by Cortisol.

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