Effects of endurance exercises on microarchitecture of proximal tibia in ovariectomized rats

Valiollah Dabidiroshan; Masomeh Nobahar

Journal of Kermanshah University of Medical Sciences

Peer-reviewed Medical Quarterly

Current Issue All Issues In Press Accepted Manuscripts Search

Journal Information Boards and Committees Indexing and Listing Sources Journal Metrics Open Peer Review (OPR)Publication Ethics and Malpractice Statement Reviewer and AE Registration Form Contact Us Support

Authors Guide Submit Manuscript

Effects of endurance exercises on microarchitecture of proximal tibia in ovariectomized rats

Author(s):

Valiollah Dabidiroshan^1,*,

Masomeh Nobahar²

1Dept. of Sport Physiology, School of Athletic Sciences, University of Mazandaran, Babolsar, Iran

2Dept. of Athletic Sciences, Payam Noor University, Iran

Journal of Kermanshah University of Medical Sciences:Vol. 15, issue 6; e78897

Published online:Mar 19, 2012

Article type:Research Article

Received:Apr 06, 2011

Accepted:Sep 13, 2011

How to Cite:Valiollah DabidiroshanMasomeh NobaharEffects of endurance exercises on microarchitecture of proximal tibia in ovariectomized rats.J Kermanshah Univ Med Sci.15(6):e78897.

Abstract

Background: Appropriate endurance exercise can change bone mass density and strength of weight-bearing bones in both animals and humans, but its effects on the microstructure are not known. This study aimed to determine skeletal changes induced by the treadmill running endurance in ovariectomized adult mice.

Methods: twenty-seven adult female rats were divided into experimental and control groups.(Each group consisted of 9 rats) and 9 rats were killed to determine baseline values. Experimental group performed the progressive running exercise for 8 weeks, 12 to 20 m/min, 10 to 59 min, 5 times per week. Microarchitecture of dense and spongy bone tissues in the proximal tibia epiphysis were measured by using a semi-automated image analysis system. Data was analyzed using t-student tests (P<0.05).

Results: Running on treadmill causes a significant increase in the thickness and volume of spongy tissue and bone tissue was dense and spongy epiphysis upper tibia (P<0.05). Compared to control, treadmill running group showed significant difference in trabecular thickness and separation.

Conclusion: Ovariectomy may decrease the microarchitecture properties of cortical tissue and especially, trabecular tissue in weight-bearing bones. Increasing bone strength induced by endurance exercise is mediated by changes in bon microarchitecture.

Keywords

weight-bearing exercise

microarchitecture

ovariectomized

Fulltext

References

1.
The references of this article is available on PDF.

comments