Advanced maternal age relationship with pregnancy complications

Farahnaz Keshavarzi; Mansour Rezaei; Shirin Iranfar; Taravat Fakheri; Anisodolleh Nankali; Azam Imani

Journal of Kermanshah University of Medical Sciences

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Advanced maternal age relationship with pregnancy complications

Author(s):

Farahnaz Keshavarzi^1,*,

Mansour Rezaei²,

Shirin Iranfar³,

Taravat Fakheri¹,

Anisodolleh Nankali¹,

Azam Imani⁴

1Dept. of Obstetrics and Gynecology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran

2Dept. of Biostatistics and Epidemiology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran

3Dept. of Medical Education, Kermanshah University of Medical Sciences, Kermanshah, Iran

4Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran

Journal of Kermanshah University of Medical Sciences:Vol. 15, issue 3; e79358

Published online:Sep 19, 2011

Article type:Research Article

Received:May 13, 2010

Accepted:Oct 19, 2010

How to Cite:Farahnaz KeshavarziMansour RezaeiShirin IranfarTaravat FakheriAnisodolleh NankaliAzam Imaniet al.Advanced maternal age relationship with pregnancy complications.J Kermanshah Univ Med Sci.15(3):e79358.

Abstract

Background: Due to increase in pregnancy complications in advanced age, this study was conducted to assess the relationship between advanced maternal age and the pregnancy complications.

Methods: Pregnant women who admitted to the Motazedi hospital in Kermanshah were included in this analytic–cross sectional study. The study group was 1178 cases that divided into two sub-groups; 35-40 year-old (914) and over 40 years old (264); and 2038 subjects of 20-25 year-old recruited as control group. Data such as maternal age, maternal and neonatal complications were extracted from hospital recorded profiles and analyzed using Chi-square, Fisher and ANOVA statistical tests.

Results: The results showed that in case groups (35-40 and over 40 year-old): eclampsia (3.7%, 2.27%), gestational diabetes (1.8%, 4.2%), placenta previa (1.1%, 1.5%), placenta abruption (1.8%, 4.2%) were higher than the control group (0.28%, 0.5%, 0.2% and 1%) respectively.

Fetal and neonatal outcomes such as intrauterine fetal death (9.6%, 14%), macrosomia (4%, 1.9%), Apgar score<7 in 5th minutes (3.1%,2.3%) and meconium passage (9.5%,2.3%), in study groups (35-40 and over 40 year-old) have been increased compare to the control group (5.2%,0.1%,0.8% and 0.9%) respectively.

Conclusion: We concluded that with increasing maternal age, eclampsia, gestational diabetes, placenta previa, placental abruption, intrauterine fetal death, and meconium passage increased, however, preterm labor and prolonged pregnancy have been reduced.

Keywords

advanced maternal age

maternal outcomes

neonatal outcomes

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