Advanced maternal age relationship with pregnancy complications

authors:

avatar Farahnaz Keshavarzi 1 , * , avatar Mansour Rezaei 2 , avatar Shirin Iranfar 3 , avatar Taravat Fakheri 1 , avatar Anisodolleh Nankali 1 , avatar Azam Imani 4

Dept. of Obstetrics and Gynecology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
Dept. of Biostatistics and Epidemiology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
Dept. of Medical Education, Kermanshah University of Medical Sciences, Kermanshah, Iran
Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran

how to cite: Keshavarzi F, Rezaei M, Iranfar S, Fakheri T, Nankali A, et al. Advanced maternal age relationship with pregnancy complications. J Kermanshah Univ Med Sci. 2011;15(3):e79358.

Abstract

Background: Due to increase in pregnancy complications in advanced age, this study was conducted to assess the relationship between advanced maternal age and the pregnancy complications.
Methods: Pregnant women who admitted to the Motazedi hospital in Kermanshah were included in this analytic–cross sectional study. The study group was 1178 cases that divided into two sub-groups; 35-40 year-old (914) and over 40 years old (264); and 2038 subjects of 20-25 year-old recruited as control group. Data such as maternal age, maternal and neonatal complications were extracted from hospital recorded profiles and analyzed using Chi-square, Fisher and ANOVA statistical tests.
Results: The results showed that in case groups (35-40 and over 40 year-old): eclampsia (3.7%, 2.27%), gestational diabetes (1.8%, 4.2%), placenta previa (1.1%, 1.5%), placenta abruption (1.8%, 4.2%) were higher than the control group (0.28%, 0.5%, 0.2% and 1%) respectively.
Fetal and neonatal outcomes such as intrauterine fetal death (9.6%, 14%), macrosomia (4%, 1.9%), Apgar score<7 in 5th minutes (3.1%,2.3%) and meconium passage (9.5%,2.3%), in study groups (35-40 and over 40 year-old) have been increased compare to  the control group (5.2%,0.1%,0.8% and 0.9%) respectively.
Conclusion: We concluded that with increasing maternal age, eclampsia, gestational diabetes, placenta previa, placental abruption, intrauterine fetal death, and meconium passage increased, however, preterm labor and prolonged pregnancy have been reduced.

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