Antibiotic sensitivity of escherichia coli isolated from urinary tract infection referred to Kermanshah central laboratory

Parviz Mohajeri; Babak Izadi; Nahid Naghshi

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Antibiotic sensitivity of escherichia coli isolated from urinary tract infection referred to Kermanshah central laboratory

Author(s):

Parviz Mohajeri^1,*,

Babak Izadi²,

Nahid Naghshi¹

1Dept. of Microbiology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran

2Dept. of Pathology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran

Journal of Kermanshah University of Medical Sciences:Vol. 15, issue 1; e79392

Published online:May 19, 2011

Article type:Research Article

Received:Feb 04, 2010

Accepted:Jul 06, 2010

How to Cite:Parviz MohajeriBabak IzadiNahid NaghshiAntibiotic sensitivity of escherichia coli isolated from urinary tract infection referred to Kermanshah central laboratory.J Kermanshah Univ Med Sci.15(1):e79392.

Abstract

Background: Escherichia coli (Ecoli) has been considered as the most common agent of urinary tract infection in all regions. Recently, increased drug resistance has been lead to some problems in treatment related diseases. So, evaluation of resistance patterns of bacteria in each region could be a valuable guide for empirical treatment.

Methods: All referred urine sample to Kermanshah Central Laboratory during 1998 that was reported positive to Ecoli were assessed. Susceptibility pattern to 19 antimicrobial agents was evaluated using Kirby Bauer method according to CLSI standards.

Results: A total of 834 Ecoli isolated from 19,208 positive urine cultures. 84% of subjects were females and 16% males. Sensitivity rate for nitrofurantoin (84%), ceftizoxime (72%), norfloxacin (70%), cefotaxime (69%), Amikacin (66%), ciprofloxacin (65%), ceftriaxone (64%), ceftazidim (55%) was higher than 50%. Sensitivity to nalidixic acid, cefexime, gentamicin, co-trimoxazole, ticarcillin, caphalexin, cephalotin, tetracycline, amoxicillin, amoxicillin clavulanate and ampicillin were determined less than 50%.

Conclusion: Nitrofurantoin and ceftizoxime are currently effective against Ecoli, although an indiscriminate use of antibiotics should be avoided because of drug resistance probable. It seems that ampicillin could be excluded from routine sensitivity testing.

Keywords

escherichia coli

UTI

drug resistance

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