Relationship between ectopic pregnancy and its risck factors

Anisodoleh Nankali; Farid Najafi; Samira Saeidi

Journal of Kermanshah University of Medical Sciences

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Relationship between ectopic pregnancy and its risck factors

Author(s):

Anisodoleh Nankali¹,

Farid Najafi^1,*,

Samira Saeidi²

1High Risk Pregnancy Center, Kermanshah University of Medical Sciences, Kermanshah, Iran

2School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran

Journal of Kermanshah University of Medical Sciences:Vol. 14, issue 2; e79519

Published online:Sep 19, 2010

Article type:Research Article

Received:Sep 08, 2009

Accepted:Jan 19, 2010

How to Cite:Anisodoleh NankaliFarid NajafiSamira SaeidiRelationship between ectopic pregnancy and its risck factors.J Kermanshah Univ Med Sci.14(2):e79519.

Abstract

Background: Ectopic pregnancy (EP) is a prevalent problem and the most common cause of maternal mortality at the first trimester. Results from different studies are not consistent regarding the risk factors associated with EP. The current study aimed to investigate about risk factors associated with EP in Kermanshah-Iran.

Methods: A case–control study conducted to compare risk factors of EP among two groups of 250 women with EP and 500 women with normal delivery or cesarean section. Both groups were compared in regards to gynecologic, obstetric and demographic factors. Using Stata, we calculated odds ratios (OR) and 95% confidence intervals (95%CI) related to each factor within a univariate and multivariate model.

Results: Using an univariate model, age, gravid >2, pariety≥3, previous abortion and EP, history of pelvic inflammatory disease (PID) and pelvic or abdominal surgery, infertility and its treatment as well as tubal ligation and use of intra uterine device were statistically associated with EP (p<0.05 for all variables). In multivariate analysis, age, history of tubal ligation, history of abdominal and pelvic surgery, cesarean section, infertility and ovulation induction were associated with EP.

Conclusion: The control of risk factors for EP can lead to decrease the burden of such condition. Future studies with larger sample size within an EP registry can effectively lead to collecting more precise data regarding factors such as smoking and PID.

Keywords

ectopic pregnancy

risk factors

case-control study

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