Cardiac manifestation of normokalemic periodic paralysis in 21 years old male in Kermanshah

Alireza Ray; Shirin Rashidi Shahpasandi; Parastou Shirvani

Journal of Kermanshah University of Medical Sciences

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Cardiac manifestation of normokalemic periodic paralysis in 21 years old male in Kermanshah

Author(s):

Alireza Ray¹,

Shirin Rashidi Shahpasandi^1,*,

Parastou Shirvani²

1Dept. of Cardiology, School of Medicine, Kermanshah University of Medical Sciences , kermanshah, Iran

2Emam Ali Hospital, Kermanshah University of Medical Sciences , kermanshah, Iran

Journal of Kermanshah University of Medical Sciences:Vol. 13, issue 4; e79590

Published online:Mar 19, 2010

Article type:Case Report

Received:Jun 24, 2009

Accepted:Nov 24, 2009

How to Cite:Alireza RayShirin Rashidi ShahpasandiParastou ShirvaniCardiac manifestation of normokalemic periodic paralysis in 21 years old male in Kermanshah.J Kermanshah Univ Med Sci.13(4):e79590.

Abstract

Background: Normokalemic periodic paralysis is an autosomal dominant disorder involving the abnormal function of skeletal muscle’s voltage-gated alpha-subunits. It is characterized by paralysis attack of varying severity with concomitant normal serum potassium concentration. Although normokalemic periodic paralysis is well established in the literature, but its cardiac manifestations are very rare.

Case Report: We present 21 years old age male, which referred to Imam Ali Hospital with severe palpitation, atypical angina and flaccid quadric paralysis.

Electrocardiographic manifestation was first-degree AV block, Bijeminated ventricular extrasystole and severe ST-T change in pericordial leads. Initial potassium level was 4 meq/l, CPK and aldolase level were normal. Echocardiography and exercise test were normal.

Conclusion: After four days administration of acetazolamide, his weakness was disappeared and ECG became normal. He discharged from hospital with normal neurological examination and effective treatment outcome.

Keywords

Normokalemic periodic paralysis

cardiac manifestations

ECG

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