Journal of Kermanshah University of Medical Sciences
Peer-reviewed Medical Quarterly
Comparing Fluconazole and Clotrimazole in treatment of candida albicans vaginitis
Abstract
Introduction and Objectives: This study was done to compare the effectiveness of Fluconazole and Clotrimazole in treatment of candida albicans vaginitis in patients referring to health centers affiliated with Shahid Beheshti University, during the year 1379.
Materials and Methods: 70 patients received either a single oral dose of 150 mg Fluconazole (35 patients) or 7 days course of vaginal Clotrimazole. Clinical history, smear, and culture were obtained.
Results: Positive Clinical and laboratory response was seen in 77% and 74% and 91% and 77% of Fluconazole and Clotrimazole groups, respectively. There was no statistically significant differences between the 2 groups regarding clinical or laboratory responses to treatment.
Discussion and Conclusions: If confirmed by others, a single oral dose of 150 mg Fluconazole should replace the 7 days course of vaginal Clotrimazole.
Copyright
© 2002, Journal of Kermanshah University of Medical Sciences. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.
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