Abstract
Background& Objectives : Pseudomonas aeruginosa is inherently resistant to many antibiotics at concentrations that can be achieved in vivo. This study was done to assess the susceptibility of P.aeruginosa strains, isolated from Kermanshahian patients, to the most commonly prescribed antibiotics.
Materials and Methods :50 clinical specimens collected and examined from July 2001 to July 2002 from three hospitals(Sina, Imam khomeini, Taleghani).
MIC90 was determined by SIGMA powders and agar dilution method for the following antibiotics:Amikacin,Azlocillin,Aztreonam,Carbenicillin,Ceftazidime,Ciprofloxacin,
Gentamicin, Imipenem, Mezlocillin, Norfloxacin, Ticarcillin and Tobramycin.
Results: Resistance to Amikacin, Azlocillin, Aztreonam, Carbenicillin, Ceftazidime, Ciprofloxacin, Gentamicin, Imipenem, Mezlocillin, Norfloxacin, Ticarcillin and Tobramycin was 38%, 52%, 80% ,72%, 50%, 38%, 52%, 10%, 98%, 40%, 90% and 46%, respectively.
Discussion : There is no significant difference between our results and others' studies. Imipenem was the most effective antibiotic against P.aeruginosa strains isolated from our patients.
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© 2004, Journal of Kermanshah University of Medical Sciences. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.